Bepridil-d5 hydrochloride
Bepridil-d5 (hydrochloride) (CERM 1978-d5) is deuterium labeled Bepridil hydrochloride. Bepridil hydrochloride (CERM 1978) is a calcium channel blocker, with antianginal activity.
For research use only. We do not sell to patients.
- Formula: C24H30D5ClN2O
- Molecular Weight:408.03
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
All Calcium Channel Isoforms
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Biological Activity
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 68099-86-5
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Molecular Weight 408.03
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Formula C24H30D5ClN2O
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SMILES
CC(COCC(CN(CC1=CC=CC=C1)C2=C(C([2H])=C(C([2H])=C2[2H])[2H])[2H])N3CCCC3)C.Cl
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Synonyms
CERM 1978-d5
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
[1]. Russak EM, et al. Impact of Deuterium Substitution on the Pharmacokinetics of Pharmaceuticals. Ann Pharmacother. 2019;53(2):211-216. [Content Brief]
[2]. Flaim SF, et al. Effects of bepridil hydrochloride on cardiocirculatory dynamics, coronary vascular resistance, and cardiac output distribution in normal, conscious rats. J Cardiovasc Pharmacol. 1988 Mar;11(3):363-72. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)