1. GPCR/G Protein Neuronal Signaling
  2. mGluR
  3. Biphenylindanone A

Biphenylindanone A  (Synonyms: BINA)

Cat. No.: HY-15442 Purity: ≥99.0%
COA Handling Instructions

Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders.

For research use only. We do not sell to patients.

Biphenylindanone A Chemical Structure

Biphenylindanone A Chemical Structure

CAS No. : 866823-73-6

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 435 In-stock
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
USD 435 In-stock
1 mg USD 130 In-stock
5 mg USD 395 In-stock
10 mg   Get quote  
50 mg   Get quote  

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This product is a controlled substance and not for sale in your territory.

Customer Review

Based on 1 publication(s) in Google Scholar

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Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1].

IC50 & Target



In Vitro

Biphenylindanone A (BINA) shows activity on glutamate-induced scintillation proximity assay [3H]IP1 hydrolysis on WT mGluR2 (EC50=1.57 μM) in the absence or presence of 5 μM glutamate[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight









Room temperature in continental US; may vary elsewhere.


-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility
In Vitro: 

DMSO : 100 mg/mL (219.99 mM; Need ultrasonic)

Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.1999 mL 10.9996 mL 21.9993 mL
5 mM 0.4400 mL 2.1999 mL 4.3999 mL
10 mM 0.2200 mL 1.1000 mL 2.1999 mL
*Please refer to the solubility information to select the appropriate solvent.
Purity & Documentation

Purity: 99.12%

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Biphenylindanone A Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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