1. GPCR/G Protein
    Neuronal Signaling
  2. mGluR
  3. Biphenylindanone A

Biphenylindanone A (Synonyms: BINA)

Cat. No.: HY-15442 Purity: >99.0%
Handling Instructions

Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders.

For research use only. We do not sell to patients.

Biphenylindanone A Chemical Structure

Biphenylindanone A Chemical Structure

CAS No. : 866823-73-6

Size Price Stock Quantity
10 mM * 1  mL in DMSO USD 395 In-stock
Estimated Time of Arrival: December 31
1 mg USD 130 In-stock
Estimated Time of Arrival: December 31
5 mg USD 395 In-stock
Estimated Time of Arrival: December 31
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Based on 1 publication(s) in Google Scholar

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Description

Biphenylindanone A (BINA) is a selective human mGluR2 (hmGluR2) potentiator for the treatment of many neurological disorders[1].

IC50 & Target[1]

mGluR2

 

In Vitro

Biphenylindanone A (BINA) shows activity on glutamate-induced scintillation proximity assay [3H]IP1 hydrolysis on WT mGluR2 (EC50=1.57 μM) in the absence or presence of 5 μM glutamate[1].

Molecular Weight

454.56

Formula

C₃₀H₃₀O₄

CAS No.

866823-73-6

SMILES

O=C(C1=CC=C(C2=CC=CC(COC3=CC4=C(C(C(C5CCCC5)C4)=O)C(C)=C3C)=C2)C=C1)O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
In solvent -80°C 6 months
  -20°C 1 month
References

Purity: >99.0%

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Keywords:

Biphenylindanone ABINAmGluRMetabotropic glutamate receptorsmGluR2hmGluR2potentiatorneurologicaldisorderInhibitorinhibitorinhibit

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Biphenylindanone A
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