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Cat. No.: HY-182007

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CA IX-IN-5

CA IX-IN-5 (compound 9) is a human carbonic anhydrase IX (hCA IX) inhibitor with a K_i of 7.4 nM against hCA IX and 25.0 nM against hCA II.CA IX-IN-5 functionally inhibits hCA IX and hCA II isoenzymes, with selectivity for hCA IX over hCA II.CA IX-IN-5 can be used for the research of breast, colorectal, glioblastoma, lung, head and neck, and cervical cancers.

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화학식: C₂₀H₂₃ClN₆O₅S
분자량:494.95

보관:

Please store the product under the recommended conditions in the Certificate of Analysis.

CA IX-IN-5 Chemical Structure

Amount: USD 0.00

* 장바구니에 담기 전 물품의 수량을 선택해 주십시오.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- 제품 설명
- In Vitro
Chemical Information
순도&문서
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

제품 설명

All Carbonic Anhydrase Isoforms :

In Vitro

CA IX-IN-5 (compound 9) (0.05-50 μM; 10 min) potently inhibits human carbonic anhydrase IX (K_i = 7.4 nM) with 3.4-fold selectivity over human carbonic anhydrase II^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .

Chemical Information

분자량 494.95
화학식 C₂₀H₂₃ClN₆O₅S
SMILES

COC1=CC(NC2=NC(NCCC3=CC=C(C=C3)S(=O)(N)=O)=NC(Cl)=N2)=CC(OC)=C1OC
선적

Room temperature in continental US; may vary elsewhere.
보관

Please store the product under the recommended conditions in the Certificate of Analysis.

순도&문서

Handling Instructions (2659 KB)

References

[1]. Varecka V, et al. Triazinyl-benzenesulfonamide derivatives as hCA IX inhibitors: Design, synthesis, and activity determination using an optimized stop-flow methodology. Bioorg Chem. 2026;170:109524. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

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