2. Metabolic Enzyme/Protease
  3. Carbonic Anhydrase
  4. CA IX-IN-5

CA IX-IN-5 (compound 9) is a human carbonic anhydrase IX (hCA IX) inhibitor with a Ki of 7.4 nM against hCA IX and 25.0 nM against hCA II.CA IX-IN-5 functionally inhibits hCA IX and hCA II isoenzymes, with selectivity for hCA IX over hCA II.CA IX-IN-5 can be used for the research of breast, colorectal, glioblastoma, lung, head and neck, and cervical cancers.

For research use only. We do not sell to patients.

CA IX-IN-5

CA IX-IN-5 Chemical Structure

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CA IX-IN-5 Related Antibodies

Top Publications Citing Use of Products

View All Carbonic Anhydrase Isoform Specific Products:

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CA CA I CA Ⅱ CA IX CA XII CA VII CA VI CA VA CA VB CA XIII CA XIV

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Description

CA IX-IN-5 (compound 9) is a human carbonic anhydrase IX (hCA IX) inhibitor with a Ki of 7.4 nM against hCA IX and 25.0 nM against hCA II.CA IX-IN-5 functionally inhibits hCA IX and hCA II isoenzymes, with selectivity for hCA IX over hCA II.CA IX-IN-5 can be used for the research of breast, colorectal, glioblastoma, lung, head and neck, and cervical cancers[1].

In Vitro

CA IX-IN-5 (compound 9) (0.05-50 μM; 10 min) potently inhibits human carbonic anhydrase IX (Ki = 7.4 nM) with 3.4-fold selectivity over human carbonic anhydrase II[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

CA IX-IN-5 Related Antibodies
Molecular Weight

494.95

Formula

C20H23ClN6O5S
SMILES

COC1=CC(NC2=NC(NCCC3=CC=C(C=C3)S(=O)(N)=O)=NC(Cl)=N2)=CC(OC)=C1OC
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
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CA IX-IN-5 Related Classifications

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The dilution calculator equation

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2
Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

Keywords:

CA IX-IN-5Carbonic AnhydraseCarbonate dehydrataseglioblastomacervical cancershead and neck cancershCA IXhCA IIbreast cancershuman carbonic anhydrase IXlung cancerscolorectal cancersInhibitorinhibitorinhibit

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CA IX-IN-5
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HY-182007
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