country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Cat. No.: HY-19418

Copy Link Print Information

KRP-101

KRP-101 is a compound that regulates the expression of genes related to lipid metabolism. It is a PPARα agonist that can highly sensitively regulate the expression of genes such as apolipoprotein A-IV, which may be related to lowering serum triglycerides and increasing HDL.

For research use only. We do not sell to patients.

CAS No.: 311770-26-0
Formula: C₂₆H₂₆FNO₅
Molecular Weight:451.49

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (262 KB)

KRP-101 Chemical Structure

CAS No.: 311770-26-0

Size

Price

Stock

Quantity

Amount: USD 0.00

* Please select Quantity before adding items.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- Cellular Effect
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

All PPAR Isoforms :

Cellular Effect

Cell Line	Type	Value	Description	References
CHO-K1	EC₅₀	0.014 μM Compound: 7	Transcriptional activation activity on human T279M-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human T279M-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.667 μM Compound: 7	Transcriptional activation activity on human I272F-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human I272F-mutant Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.00061 μM Compound: 7	Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.61 nM Compound: 7	Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells Transcriptional activation activity on human Peroxisome proliferator activated receptor alpha expressed in CHO-K1 cells	[PMID: 12951082]
CHO-K1	EC₅₀	0.013 μM Compound: KRP-101	Transactivation of human PPARalpha expressed in CHO-K1 cells Transactivation of human PPARalpha expressed in CHO-K1 cells	[PMID: 22133631]
CHO-K1	EC₅₀	1.92 μM Compound: KRP-101	Transactivation of human PPARdelta expressed in CHO-K1 cells Transactivation of human PPARdelta expressed in CHO-K1 cells	[PMID: 22133631]
CHO-K1	EC₅₀	2.5 μM Compound: KRP-101	Transactivation of human PPARgamma expressed in CHO-K1 cells Transactivation of human PPARgamma expressed in CHO-K1 cells	[PMID: 22133631]

Chemical Information

CAS No. 311770-26-0
Molecular Weight 451.49
Formula C₂₆H₂₆FNO₅
SMILES

FC(C=C1)=CC=C1OC(C=C2)=CC=C2CNC(C3=C(C=CC(C[C@H](CC)C(O)=O)=C3)OC)=O
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (262 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Highly sensitive upregulation of apolipoprotein A-IV by peroxisome proliferator-activated receptor alpha (PPARalpha) agonist in human hepatoma cells

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Dilution Calculator

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

MOQ

Minimum order quantity

100 mg

Get Quote In-stock

Other size

Get Quote

Amount: USD 0.00

Biological Activity
- Description
Chemical Information
Purity & Documentation
References

Product Name:
Cat. No.:
Quantity:
MCE Japan Authorized Agent:

Product Name:
CAS No.:
Species:
Purity:
Quantity:

KRP-101

All PPAR Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

KRP-101 Related Classifications

HY-19418 Related Classifications