Risimtinib
Risimtinib (Risimtinibum) is a FGFR1 inhibitor with an IC50 of 2.1 nM. Risimtinib inhibits the proliferation of FGFR1-positive cancer cells. Risimtinib is used for the research of myeloid leukemia.
For research use only. We do not sell to patients.
- CAS No.: 2126751-11-7
- Formula: C30H31N5O3
- Molecular Weight:509.60
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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FGFR1 2.1 nM (IC50) |
Risimtinib (compound 19a) potently inhibits purified FGFR1 kinase activity with an IC50 of 2.1 nM[1].
Risimtinib inhibits the proliferation of FGFR1-translocated KG-1 leukemia cells with an IC50 of 14.9 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2126751-11-7
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Molecular Weight 509.60
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Formula C30H31N5O3
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SMILES
CNC(C1=CC=CC2=C1C=CC(OC3=CC=NC(NC(C4=CC=C(N5C[C@H](N[C@H](C5)C)C)C=C4)=O)=C3)=C2)=O
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Synonyms
Risimtinibum
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Risimtinib Related Classifications
HY-184094 Related Classifications
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