S-6123
S-6123 is a potent antimicrobial compound of the oxazolidinone series. S-6123 inhibits ribosomal protein synthesis without inhibiting DNA or RNA synthesis.
For research use only. We do not sell to patients.
- CAS No.: 87508-45-0
- Formula: C10H12N2O5S
- Molecular Weight:272.28
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Help & FAQs
All Antibiotic Isoforms
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Biological Activity
Description
IC50 & Target
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Oxazolidinone |
In Vitro
S-6123 exhibits potent antimicrobial activity against gram-positive bacterias, Streptococcus pyogenes; Streptococcus agalactiae; Group C and G streptococci; Viridans group streptococci, penicillin susceptible; and Viridans group streptococci, penicillin resistant with MIC values of 16 μg/ml; 32 μg/ml; 16 μg/ml; 16 μg/ml; 8 μg/ml; 32 μg/ml, respectively.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. Further protocols information, click here.
Chemical Information
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CAS No. 87508-45-0
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Molecular Weight 272.28
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Formula C10H12N2O5S
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SMILES
O=S(C1=CC=C(C=C1)N2C(O[C@H](C2)CO)=O)(N)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Protocols
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Research Protocol for Infectious Diseases
Infectious-disease experiments test how pathogens interact with host barriers, innate immune receptors, inflammatory signaling, pathogen replication, and tissue injury; pattern-recognition receptors such as TLRs, RIG-I-like receptors, NOD-like receptors, and inflammasomes detect microbial molecules and activate NF-κB, interferon, and cytokine responses. The central hypothesis is that infection severity reflects the balance between pathogen burden and host response: protective inflammation restricts pathogen growth, whereas excessive or mislocalized inflammation contributes to tissue damage and disease phenotype. Unresolved questions include which host pathways are protective versus pathogenic, why some infection models fail to translate to human disease, and which combined readouts best predict clinically relevant infection outcomes.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
S-6123 Related Classifications
HY-122123 Related Classifications
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