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Cat. No.: HY-156108

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2-Chlorophenoxazine

2-Chlorophenoxazine is a Akt inhibitor with an IC₅₀ value of 2-5 μM for in vitro. 2-Chlorophenoxazine can induce apoptosis. 2-Chlorophenoxazine can be used for cancer diseases research.

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CAS No.: 56821-03-5
Formule: C₁₂H₈ClNO
Masse moléculaire:217.65

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (267 KB)

2-Chlorophenoxazine Chemical Structure

CAS No.: 56821-03-5

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
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Activité biologique

Description

Voir tous les produits spécifiques à Isoform Akt :

Cellular Effect

Cell Line	Type	Value	Description	References
K562	IC₅₀	>30 μM Compound: 28	Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis Antiproliferative activity against human K562 cells after 48 hrs by hemocytometric analysis	[PMID: 21563750]

Chemical Information

CAS No. 56821-03-5
Masse moléculaire 217.65
Formule C₁₂H₈ClNO
SMILES

ClC(C=C1N2)=CC=C1OC3=C2C=CC=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (267 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Thimmaiah KN, et al. Identification of N10-substituted phenoxazines as potent and specific inhibitors of Akt signaling. J Biol Chem. 2005 Sep 9;280(36):31924-35 [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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2-Chlorophenoxazine

Voir tous les produits spécifiques à Isoform Akt