AA43279
Based on 1 Customer Validation
AA43279 is an in gamma-aminobutyric acid (GABA) fast-firing interneurons located activator for Nav1.1 channel (SCN1A) with an EC50 of 9.5 μM. AA43279 enhances specific neuronal firing activity in vitro, and exhibits anticonvulsant activity in rat MEST model.
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- Pureté: 98.00%
- CAS No.: 354812-16-1
- Formule: C12H12N2O2S
- Masse moléculaire:248.31
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Activité biologique
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Nav1.1 9.5 μM (IC50) |
Nav1.6 11.6 μM (IC50) |
Nav1.5 14.4 μM (IC50) |
Nav1.2 22.8 μM (IC50) |
Chemical Information
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CAS No. 354812-16-1
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Appearance Solid
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Masse moléculaire 248.31
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Formule C12H12N2O2S
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Color Light yellow to light brown
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SMILES
O=C(C1=C(N)C=C(C2=CC=C(OC)C=C2)S1)N
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 6.67 mg/mL (26.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0272 mL | 20.1361 mL | 40.2722 mL | 100.6806 mL |
| 5 mM | 0.8054 mL | 4.0272 mL | 8.0544 mL | 20.1361 mL | |
| 10 mM | 0.4027 mL | 2.0136 mL | 4.0272 mL | 10.0681 mL | |
| 15 mM | 0.2685 mL | 1.3424 mL | 2.6848 mL | 6.7120 mL | |
| 20 mM | 0.2014 mL | 1.0068 mL | 2.0136 mL | 5.0340 mL | |
| 25 mM | 0.1611 mL | 0.8054 mL | 1.6109 mL | 4.0272 mL |
AA43279 Related Classifications
HY-125928 Related Classifications
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