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Cat. No.: HY-18037

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AMG-7980

AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a K_D of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope.

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CAS No.: 947192-73-6
Formule: C₁₉H₂₂N₄O₂
Masse moléculaire:338.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

AMG-7980 Chemical Structure

CAS No.: 947192-73-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

AMG-7980 exhibits high affinity to phosphodiesterase 10A (PDE10A), with a K_D of 0.94 nM. AMG-7980 can be used as a tracer of PDE10A, when labeled with radioactive isotope^[1].

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Chemical Information

CAS No. 947192-73-6
Masse moléculaire 338.40
Formule C₁₉H₂₂N₄O₂
SMILES

CC1=CC(C2=C3C=C(OC)C(OC)=CC3=NN=C2)=CN=C1NC(C)C
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Hu E, et al., Rapid identification of a novel small molecule phosphodiesterase 10A (PDE10A) tracer. J Med Chem. 2012 May 24;55(10):4776-87. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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AMG-7980

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Activité biologique

Description

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

AMG-7980 Related Classifications

HY-18037 Related Classifications

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