Bakuchicin
Bakuchicin (Allopsoralen) is a compound that can be found in Psoralea corylifolia. It has certain inhibitory activity against topoisomerase II. In the cell model infected with Simian virus 40 (SV40), the IC50 of Bakuchicin against topoisomerase II is 404 μM. Bakuchicin can be used in the research of the anti-infection field.
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- CAS No.: 4412-93-5
- Formule: C11H6O3
- Masse moléculaire:186.16
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
IC50 & Target
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Topoisomerase II 404 μM (IC50) |
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
404 μM
Compound: 6
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Inhibition of DNA topoisomerase 2 in human HeLa cells by kinetoplast DNA decantation assay
Inhibition of DNA topoisomerase 2 in human HeLa cells by kinetoplast DNA decantation assay
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[PMID: 9544566] |
Chemical Information
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CAS No. 4412-93-5
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Masse moléculaire 186.16
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Formule C11H6O3
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SMILES
O=C1C=CC2=C(C=CC3=C2OC=C3)O1
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Synonyms
Allopsoralen
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)