BMS 753 (Standard)
BMS 753 (Standard) is the analytical standard of BMS 753 (HY-107395). This product is intended for research and analytical applications. BMS 753 is an isotype-selective retinoic acid receptor α (RARα) agonist, with a Ki of 2 nM.
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- CAS No.: 215307-86-1
- Formule: C21H21NO4
- Masse moléculaire:351.40
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
RARα[1]
Chemical Information
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CAS No. 215307-86-1
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Masse moléculaire 351.40
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Formule C21H21NO4
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SMILES
O=C(O)C1=CC=C(NC(C2=CC3=C(C(C)(C)C(C3(C)C)=O)C=C2)=O)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. M Géhin, et al. Structural basis for engineering of retinoic acid receptor isotype-selective agonists and antagonists. Chem Biol. 1999 Aug;6(8):519-29. [Content Brief]
[2]. R Taneja, et al. Cell-type and promoter-context dependent retinoic acid receptor (RAR) redundancies for RAR beta 2 and Hoxa-1 activation in F9 and P19 cells can be artefactually generated by gene knockouts. Proc Natl Acad Sci U S A. 1996 Jun 11; 93(12): 6197-6202. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)