ERβ agonist-2
ERβ agonist-2 (Page 72) is a selective ERβ agonist with an EC50 of 800 nM or lower. ERβ agonist-2 selectively inhibits T cell activation and/or proliferation, thereby reducing circulating T cell levels in subjects, without exerting significant effects on circulating neutrophil, monocyte or B cell levels. ERβ agonist-2 is applicable to studies of chronic heart failure after myocardial infarction, as well as graft-versus-host disease, multiple sclerosis and experimental autoimmune encephalomyelitis.
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- CAS No.: 628321-25-5
- Formule: C19H16N2O2
- Masse moléculaire:304.34
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
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ERβ 800 or low nM (EC50) |
ERβ agonist-2 exhibits an EC50 of 800 nM or less at estrogen receptor β (ERβ)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 628321-25-5
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Masse moléculaire 304.34
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Formule C19H16N2O2
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SMILES
OC1=CC=C(C2=C(C3=C(C)ON=C3C)NC4=C2C=CC=C4)C=C1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)