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Cat. No.: HY-120082

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FR-182980

FR-182980 is an orally active ACAT1 inhibitor (IC₅₀: 30 nM). FR-182980 has hypocholesterolemic activity and can be used for research of atherosclerosis.

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CAS No.: 179054-51-4
Formule: C₂₉H₃₄FN₃O₂S₂
Masse moléculaire:539.73

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

FR-182980 Chemical Structure

CAS No.: 179054-51-4

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

FR-182980 is an orally active ACAT1 inhibitor (IC₅₀: 30 nM). FR-182980 has hypocholesterolemic activity and can be used for research of atherosclerosis^[1].

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Chemical Information

CAS No. 179054-51-4
Masse moléculaire 539.73
Formule C₂₉H₃₄FN₃O₂S₂
SMILES

O=C(NC1=C(SC)C=C(C)N=C1SC)N(C2CCCCCC2)CC3=CC=C(OC4=CC=C(F)C=C4)C=C3
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Tanaka A, et al. Inhibitors of acyl-CoA:cholesterol O-acyltransferase (ACAT). Part 1: identification and structure-activity relationships of a novel series of substituted N-alkyl-N-biphenylylmethyl-N'-arylureas. Bioorg Med Chem. 1998 Jan;6(1):15-30. [Content Brief]

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Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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FR-182980

Voir tous les produits spécifiques à Isoform Acyltransferase