GRL-8234
GRL-8234 is a potent β-secretase (BACE1) inhibitor with blood-brain barrier penetration (Ki = 1.8 nM). GRL-8234 can rescue age-related cognitive decline in Tg2576 mice. GRL-8234 can be used in the research related to Alzheimer's disease (AD).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 913071-81-5
- Formule: C36H42N4O6S
- Masse moléculaire:658.81
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
- Pureté et documentation
- Références
-
Help & FAQs
Activité biologique
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CHO | IC50 |
0.001 μM
Compound: 24, GRL-8234
|
Inhibition of memapsin 2 expressed in CHO cells
Inhibition of memapsin 2 expressed in CHO cells
|
[PMID: 18180160] |
Chemical Information
-
CAS No. 913071-81-5
-
Masse moléculaire 658.81
-
Formule C36H42N4O6S
-
SMILES
O=S(N(C)C1=CC(C(N[C@@H](CC2=CC=CC=C2)[C@@H](CNCC3=CC(OC)=CC=C3)O)=O)=CC(C(N[C@H](C)C4=CC=CC=C4)=O)=C1)(C)=O
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GRL-8234 Related Classifications
HY-10104 Related Classifications
Powered by Bioz