GW0072
GW0072 is a partial agonist of PPARγ and does not directly bind to the AF-2 helix of PPARγ, resulting in specific partial receptor transcriptional activation properties.
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- CAS No.: 321557-86-2
- Formule: C37H46N2O4S
- Masse moléculaire:614.84
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Chemical Information
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CAS No. 321557-86-2
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Masse moléculaire 614.84
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Formule C37H46N2O4S
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SMILES
O=C(C1=CC=C(C=C1)CCCCN2[C@@H](S[C@H](C2=O)CC(N(CC3=CC=CC=C3)CC4=CC=CC=C4)=O)CCCCCCC)O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
[1]. Ligand entry pathways in the ligand binding domain of PPARc receptor
[2]. Genest D, et al. Ligand-escape pathways from the ligand-binding domain of PPARgamma receptor as probed by molecular dynamics simulations. Eur Biophys J. 2008 Apr;37(4):369-79. [Content Brief]
[3]. Zhang F, et al. Selective Modulators of PPAR-gamma Activity: Molecular Aspects Related to Obesity and Side-Effects. PPAR Res. 2007;2007:32696. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
GW0072 Related Classifications
HY-118097 Related Classifications
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