HBX 28258
HBX 28258 is a selective USP7 inhibitor, with an IC50 of 22.6 μM. HBX 28258 can covalently binds to Cys223 located in the catalytic core of USP7, inhibits its deubiquitinating activity, promotes MDM2 protein degradation, and activates p53.
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- CAS No.: 1426544-54-8
- Formule: C26H30ClN3O
- Masse moléculaire:435.99
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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Chemical Information
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Help & FAQs
Activité biologique
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USP7 22.6 μM (IC50) |
Chemical Information
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CAS No. 1426544-54-8
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Masse moléculaire 435.99
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Formule C26H30ClN3O
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SMILES
O=C(C1=CC2=C(N=C3C(CCCC3)=C2Cl)C=C1)NCCCN(CC)CC4=CC=CC=C4
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
HBX 28258 Related Classifications
HY-124739 Related Classifications
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