Idasanutlin-d3-1
Based on 1 Customer Validation
Idasanutlin-d3-1 (RG7388-d3-1) is the deuterium labeled Idasanutlin. Idasanutlin is a potent antagonist of MDM2/p53. Idasanutlin inhibits relapsed or refractory acute myeloid leukemia.
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- Pureté: 99.57%
- Formule: C31H26D3Cl2F2N3O4
- Masse moléculaire:619.50
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
1. This compound can be used as a tracer
2. This compound can be used as an internal standard for quantitative analysis by NMR, GC-MS, or LC-MS.
Chemical Information
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Unlabeled Cas 1229705-22-9
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Appearance Solid
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Masse moléculaire 619.50
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Formule C31H26D3Cl2F2N3O4
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Color White to off-white
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SMILES
O=C(NC1=C(OC([2H])([2H])[2H])C=C(C(O)=O)C=C1)[C@H](N[C@H]2CC(C)(C)C)[C@H](C3=CC=CC(Cl)=C3F)[C@@]2(C#N)C4=CC=C(Cl)C=C4F
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Synonyms
RG7388-d3-1
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 100 mg/mL (161.42 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (279 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6142 mL | 8.0710 mL | 16.1421 mL | 40.3551 mL |
| 5 mM | 0.3228 mL | 1.6142 mL | 3.2284 mL | 8.0710 mL | |
| 10 mM | 0.1614 mL | 0.8071 mL | 1.6142 mL | 4.0355 mL | |
| 15 mM | 0.1076 mL | 0.5381 mL | 1.0761 mL | 2.6903 mL | |
| 20 mM | 0.0807 mL | 0.4036 mL | 0.8071 mL | 2.0178 mL | |
| 25 mM | 0.0646 mL | 0.3228 mL | 0.6457 mL | 1.6142 mL | |
| 30 mM | 0.0538 mL | 0.2690 mL | 0.5381 mL | 1.3452 mL | |
| 40 mM | 0.0404 mL | 0.2018 mL | 0.4036 mL | 1.0089 mL | |
| 50 mM | 0.0323 mL | 0.1614 mL | 0.3228 mL | 0.8071 mL | |
| 60 mM | 0.0269 mL | 0.1345 mL | 0.2690 mL | 0.6726 mL | |
| 80 mM | 0.0202 mL | 0.1009 mL | 0.2018 mL | 0.5044 mL | |
| 100 mM | 0.0161 mL | 0.0807 mL | 0.1614 mL | 0.4036 mL |
Idasanutlin-d3-1 Related Classifications
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