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Cat. No.: HY-148172

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L-Fd4A

L-Fd4A is an adenine derivative. L-Fd4A has anti-human immunodeficiency virus (HIV) (EC₅₀=1.5 μM) and anti-hepatitis B virus (HBV) (EC₅₀=1.7 μM) activity. L-Fd4A has low cytotoxicity.

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CAS No.: 210474-65-0
Formule: C₁₀H₁₀FN₅O₂
Masse moléculaire:251.22

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

L-Fd4A Chemical Structure

CAS No.: 210474-65-0

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
- In Vitro
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform HIV :

Cellular Effect

Cell Line	Type	Value	Description	References
CCRF-CEM	IC₅₀	>100 μM Compound: 36	Inhibitory activity was evaluated on mitochondrial DNA content of CEM cells Inhibitory activity was evaluated on mitochondrial DNA content of CEM cells	[PMID: 10197975]
PBMC	IC₅₀	>100 μM Compound: 36	Inhibitory activity was evaluated in human peripheral blood mononuclear (PBM) cells infected with Human immunodeficiency virus-1 Inhibitory activity was evaluated in human peripheral blood mononuclear (PBM) cells infected with Human immunodeficiency virus-1	[PMID: 10197975]
Vero	IC₅₀	>100 μM Compound: 36	Inhibitory activity was evaluated in Vero cells. Inhibitory activity was evaluated in Vero cells.	[PMID: 10197975]

In Vitro

L-Fd4A (compound 36) has no toxicity in PBM, Vero and CEM cells. L-Fd4A shows any effect on mitochondrial DNA of CEM cells upon long-term exposure^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 210474-65-0
Masse moléculaire 251.22
Formule C₁₀H₁₀FN₅O₂
SMILES

OC[C@@H]1O[C@H](N2C3=NC=NC(N)=C3N=C2)C(F)=C1
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Lee K, et, al. Synthesis and anti-HIV and anti-HBV activities of 2'-fluoro-2', 3'-unsaturated L-nucleosides. J Med Chem. 1999 Apr 8;42(7):1320-8. [Content Brief]

Calculators

Calculateur de molarité

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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- In Vitro
Chemical Information
Pureté et documentation
Références

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L-Fd4A

Voir tous les produits spécifiques à Isoform HIV

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

L-Fd4A Related Classifications

HY-148172 Related Classifications