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LM-299

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Based on 1 Customer Validation

LM-299 is a bispecific antibody targeting PD-1 and VEGF with anti-tumor activity. The dual binding activity of LM-299 is achieved through the effective binding of its Fab-terminal anti-VEGF-A antibody to human VEGF-A, as well as the blocking effect of its Fc-terminal anti-PD-1 antibody on the PD-1/PD-L1 pathway. LM-299 binds to and modulates PD-1 and VEGF. LM-299 can be used in studies related to advanced malignant tumors, advanced solid tumors, and advanced non-small cell lung cancer.

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  • Pureté: 95.78%
  • Masse moléculaire:175.49 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for LM-299
  • Experimental Validation Results for LM-299
  • Experimental Validation Results for LM-299
  • LM-299 Chemical Structure
    LM-299 Chemical Structure
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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LM-299 Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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100 mg

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Assay Types
  • 1/16

    Tetravalent IgG-VHH

  • 1/16

    Immobilized Human PD-1 Protein, His Tag can bind LM-299. The EC50 for this effect is 164.3 ng/mL.

  • 1/16

    Immobilized Human VEGF165 Protein,hFc Tag can bind LM-299. The EC50 for this effect is 77.9 ng/mL.

  • LM-299 Chemical Structure
    1/16
  • LM-299
  • Immobilized Human PD-1 Protein, His Tag can bind LM-299. The EC50 for this effect is 164.3 ng/mL.
  • Immobilized Human VEGF165 Protein,hFc Tag can bind LM-299. The EC50 for this effect is 77.9 ng/mL.
  • Tetravalent IgG-VHH