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Cat. No.: HY-10030

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Mardepodect succinate

(Synonyms: PF-2545920 succinate)

2 Cited Publications

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Based on 2 publication(s) in Google Scholar

Mardepodect succinate (PF-2545920 succinate) is a potent and specific phosphodiesterase 10A (PDE10A) inhibitor with potential activity in the treatment of schizophrenia. Mardepodect succinate has been further optimized to improve brain penetration and compound-like properties for use in schizophrenia research.

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CAS No.: 1037309-45-7
Formule: C₂₉H₂₆N₄O₅
Masse moléculaire:510.54

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

Mardepodect succinate Chemical Structure

CAS No.: 1037309-45-7

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE) :

Chemical Information

CAS No. 1037309-45-7
Masse moléculaire 510.54
Formule C₂₉H₂₆N₄O₅
SMILES

CN(N=C1C2=CC=C(OCC3=NC4=CC=CC=C4C=C3)C=C2)C=C1C5=CC=NC=C5.O=C(O)CCC(O)=O
Synonyms

PF-2545920 succinate
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (2)

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Toxicol Appl Pharmacol

In silico and in vitro assessment of drugs potentially causing adverse effects by inhibiting CYP17A1. [Abstract]

2024 May:486:116945. PMID: 38688424
bioRxiv

2025 March 17.

Pureté et documentation

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Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Discovery of a novel class of phosphodiesterase 10A inhibitors and identification of clinical candidate 2-[4-(1-methyl-4-pyridin-4-yl-1H-pyrazol-3-yl)-phenoxymethyl]-quinoline (PF-2545920) for the treatment of schizophrenia

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

Mardepodect succinate

2 Cited Publications

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Mardepodect succinate

Publications Citing Use of MedChemExpress (MCE) Mardepodect succinate

Voir tous les produits spécifiques à Isoform Phosphodiesterase (PDE)

Activité biologique

Chemical Information

Publications (2)

Pureté et documentation

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Mardepodect succinate Related Classifications

HY-10030 Related Classifications