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Cat. No.: HY-162711

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Methylbiocin

Methylbiocin is an ATP competitive inhibitor for human CMG helicase with an IC₅₀ of 59 µM. Methylbiocin exhibits potential in cancer research.

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CAS No.: 23370-12-9
Formule: C₃₆H₄₀N₂O₁₁
Masse moléculaire:676.71

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

Methylbiocin Chemical Structure

CAS No.: 23370-12-9

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Methylbiocin is an ATP competitive inhibitor for human CMG helicase with an IC₅₀ of 59 µM. Methylbiocin exhibits potential in cancer research^[1].

IC₅₀ & Target

Helicase

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis :

Chemical Information

CAS No. 23370-12-9
Masse moléculaire 676.71
Formule C₃₆H₄₀N₂O₁₁
SMILES

CC1=C(O[C@H]2[C@H](O)[C@H](OC(C3=CC=C(C)N3)=O)[C@@H](OC)C(C)(C)O2)C=CC4=C1OC(C(NC(C5=CC(C/C=C(C)/C)=C(O)C=C5)=O)=C4O)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Xiang S, et al., Identification of ATP-Competitive Human CMG Helicase Inhibitors for Cancer Intervention that Disrupt CMG-Replisome Function. Mol Cancer Ther. 2024 Jul 10. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Methylbiocin

Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Methylbiocin Related Classifications

HY-162711 Related Classifications