MMV688844
MMV688844 is a potent Mycobacterium abscessus (Mabs) DNA Gyrase inhibitor with an IC50 value of 2 μM. MMV688844 has bactericidal properties against Mabs bamboo with a MIC50 of 12 μM. MMV688844 can be used for researching anti-bacteria.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 2650213-59-3
- Formule: C23H25ClN4O2
- Masse moléculaire:424.92
-
Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Voir tous les produits spécifiques à Isoform DNA/RNA Synthesis
More
Activité biologique
IC50: 2 μM (Mabs DNA Gyrase)[1]
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
>25 μM
Compound: 47; MMV688844
|
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay
Cytotoxicity against human HeLa cells assessed as reduction in cell viability after 48 hrs by resazurin dye based fluorescence assay
|
[PMID: 30647879] |
Chemical Information
-
CAS No. 2650213-59-3
-
Masse moléculaire 424.92
-
Formule C23H25ClN4O2
-
SMILES
O=C(C1CCN(CCC2=CC=C(Cl)C=C2)CC1)NC3=CC=NC4=CC=C(OC)N=C34
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)