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Ordesekimab

(Synonyms: AMG 714; PRV-015)
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Based on 1 Customer Validation

Ordesekimab (AMG 714; PRV-015) is a fully human IgG1κ anti-IL-15 (Interleukin Related) monoclonal antibody. The binding of Ordesekimab to IL-15 inhibits the interaction of IL-15 with the IL-2Rβ and common γ chain of the IL-15 receptor complex, but not with the IL-15Rα chain. Ordesekimab has the potential for study of nonresponsive celiac disease (NRCD).

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  • Pureté : 99.08%
  • CAS No.: 879293-15-9
  • Masse moléculaire:145.12 kDa
  • Stockage:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Ordesekimab
  • Experimental Validation Results for Ordesekimab
  • Experimental Validation Results for Ordesekimab
  • Ordesekimab Chemical Structure
    Ordesekimab Chemical Structure
CAS No.: 879293-15-9
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Ordesekimab Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Human IL-15, His Tag can bind Ordesekimab. The EC50 for this effect is 62 ng/mL.

  • 1/16

    Flow Cytometry analysis of Hela cells labelling IL-15 (red) with Ordesekimab (anti-IL-15) (HY-P99410). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.

  • Ordesekimab Chemical Structure
    1/16
  • Ordesekimab
  • Immobilized Human IL-15, His Tag can bind Ordesekimab. The EC50 for this effect is 62 ng/mL.
  • Flow Cytometry analysis of Hela cells labelling IL-15 (red) with Ordesekimab (anti-IL-15) (HY-P99410). Goat Anti-Human IgG (Alexa Fluor 488) (HY-P83776) at a dilution of 1/1000 was used as the secondary antibody. Blue-Human IgG1 kappa (HY-P99001). Black-Unlabelled control, cells without incubation with primary antibody.