(R)-HH2853
(R)-HH2853 is a mutant EZH2 inhibitor with an IC50 of <100 nM for EZH2-Y641F. (R)-HH2853 can be used for cancer and autoimmune diseases (WO2018045971A1; compound 201).
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- CAS No.: 2202678-06-4
- Formule: C31H36F3N7O3
- Masse moléculaire:611.66
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
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EZH2 Y641F mutant type <100 nM (IC50) |
Chemical Information
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CAS No. 2202678-06-4
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Masse moléculaire 611.66
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Formule C31H36F3N7O3
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SMILES
C[C@@H](N1CCN(CC1)CC(F)(F)F)C2=C(C)C(C(NCC3=C(C=C(NC3=O)C)OC)=O)=CC4=C(C5=CC=C(N=N5)C)C=CN24
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)