(rac)-Nerandomilast
Based on 1 Customer Validation
(rac)-Nerandomilast ((rac)-BI 1015550) is a mixture of enantiomeric isomers of Nerandomilast (HY-153192), among which only the (R)-enantiomer (i.e., Nerandomilast) has PDE4B inhibitory activity; the (S)-enantiomer (i.e., (S)-Nerandomilast (HY-153192B)) is basically inactive.
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- Pureté: 99.65%
- CAS No.: 1423719-27-0
- Formule: C20H25ClN6O2S
- Masse moléculaire:448.97
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Stockage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Activité biologique
Chemical Information
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CAS No. 1423719-27-0
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Appearance Solid
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Masse moléculaire 448.97
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Formule C20H25ClN6O2S
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Color Off-white to light yellow
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SMILES
O=S1C2=C(CC1)N=C(N3CCC(CC3)C4=NC=C(C=N4)Cl)N=C2NC5(CO)CCC5
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Synonyms
(rac)-BI 1015550
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvant et solubilité
DMSO : 6.67 mg/mL (14.86 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (247 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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Instruction de manipulation (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2273 mL | 11.1366 mL | 22.2732 mL | 55.6830 mL |
| 5 mM | 0.4455 mL | 2.2273 mL | 4.4546 mL | 11.1366 mL | |
| 10 mM | 0.2227 mL | 1.1137 mL | 2.2273 mL | 5.5683 mL |