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Remigromig

(Synonyms: EYE-103; MK-3000)
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Remigromig (EYE-103; MK-3000) is a humanized dual-target monoclonal antibody that targets LRP5 and FZD4. Remigromig activates the Wnt/β-catenin signaling pathway by mimicking the natural ligand Norrin, induces tight junction formation and restores blood-retinal barrier function. Administered via intravitreal injection, Remigromig reduces retinal vascular leakage, and demonstrates improvements in best-corrected visual acuity and reductions in retinal thickness in studies of diabetic macular edema. Remigromig can be used for research related to macular degeneration.

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  • Pureté: 95.25%
  • CAS No.: 3059389-31-7
  • Masse moléculaire:199.68 kDa
  • Stockage:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Remigromig
  • Experimental Validation Results for Remigromig
  • Experimental Validation Results for Remigromig
  • Remigromig Chemical Structure
    Remigromig Chemical Structure
CAS No.: 3059389-31-7
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Remigromig Product Recommendations:

To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
Trouvez votre distributeur local Your local distributor: Hycultec GmbHHycultec
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    Immobilized Frizzled-4/CD344 Protein, Human (HEK293, HY-P74140) can bind Remigromig. The ED50 for this effect is 17.22 ng/mL.

  • 1/16

    Immobilized LRP-5 Protein, Human (HEK293, HY-P77989) can bind Remigromig. The ED50 for this effect is 891.6 ng/mL.

  • Remigromig Chemical Structure
    1/16
  • Remigromig
  • Immobilized Frizzled-4/CD344 Protein, Human (HEK293, HY-P74140) can bind Remigromig. The ED50 for this effect is 17.22 ng/mL.
  • Immobilized LRP-5 Protein, Human (HEK293, HY-P77989) can bind Remigromig. The ED50 for this effect is 891.6 ng/mL.
  • Product Image