(S)-Pomalidomide
(S)-Pomalidomide ((S)-CC-4047) is an angiogenesis-inhibiting drug with growth-inhibitory activity against B-cell tumors. (S)-Pomalidomide can induce complete tumor regression in BurKitt lymphoma cells. (S)-Pomalidomide serves as an immunomodulator with potential applications in inhibiting hematological malignancies.
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- CAS No.: 202271-89-4
- Formule: C13H11N3O4
- Masse moléculaire:273.24
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
Description
Cellular Effect
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| PBMC | IC50 |
3.9 nM
Compound: (S)-5a
|
Inhibition of lipopolysaccharide stimulated TNF-alpha release in human PBMC
Inhibition of lipopolysaccharide stimulated TNF-alpha release in human PBMC
|
[PMID: 10386948] |
Chemical Information
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CAS No. 202271-89-4
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Masse moléculaire 273.24
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Formule C13H11N3O4
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SMILES
O=C1N([C@@H](CC2)C(NC2=O)=O)C(C3=C1C=CC=C3N)=O
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Synonyms
(S)-CC-4047
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)