U 88204
U 88204 is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 of 0.25 μM. U 88204 blocks HIV-1 replication in infected cells. U 88204 can be used for the research on HIV-infection and of acquired immunodeficiency syndrome (AIDs).
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- CAS No.: 136816-76-7
- Formule: C21H25N5O
- Masse moléculaire:363.47
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
10 μM
Compound: 4
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Cytotoxic concentration against MT-2 cells
Cytotoxic concentration against MT-2 cells
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[PMID: 7684450] |
U 88204 (compound 11) potently blocks HIV-1 replication in MT-2/IIIb, PBMC/D34, and H9/IIIb cells with ED50 values of 0.3 μM, 0.001 μM, and 0.04 μM, respectively, while showing low cytotoxicity (CC50 > 10 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 136816-76-7
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Masse moléculaire 363.47
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Formule C21H25N5O
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SMILES
O=C(C1=CC=2C=CC=CC2N1)N3CCN(C4=NC=CC=C4NC(C)C)CC3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
U 88204 Related Classifications
HY-180417 Related Classifications
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