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Cat. No.: HY-W040167

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VPC 23153

VPC 23153 is a S1P₄ receptor agonist and vasoconstrictor. VPC 23153 activates the S1P₄ receptor, thereby triggering vasoconstriction. VPC 23153 induces pulmonary artery contraction. VPC 23153 can be used in studies related to pulmonary arterial hypertension.

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CAS No.: 787582-98-3
Formule: C₁₇H₂₈N₃O₄P
Masse moléculaire:369.40

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Please store the product under the recommended conditions in the Certificate of Analysis.

VPC 23153 Chemical Structure

CAS No.: 787582-98-3

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Description

IC₅₀ & Target^[1]

S1PR4

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In Vitro

VPC 23153 (0.01-3 μM) induces dose-dependent vasoconstriction in isolated perfused normotensive rat lungs^[1].
VPC 23153 (0.1-10 μM) induces concentration-dependent contraction of isolated pulmonary arteries (but not renal or mesenteric arteries) from chronically hypoxic rats^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 787582-98-3
Masse moléculaire 369.40
Formule C₁₇H₂₈N₃O₄P
SMILES

[C@@H](COP(=O)(O)O)(N)C=1NC=2C(N1)=CC=C(CCCCCCCC)C2
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Ota H, et al. S1P(4) receptor mediates S1P-induced vasoconstriction in normotensive and hypertensive rat lungs. Pulm Circ. 2011;1(3):399-404. [Content Brief]

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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VPC 23153

Voir tous les produits spécifiques à Isoform LPL Receptor

Activité biologique

Chemical Information

Pureté et documentation

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Calculators

Help & FAQs

VPC 23153 Related Classifications

HY-W040167 Related Classifications