Calpain-1 (pig)
Based on 1 publication(s) in Google Scholar
Calpain-1 (pig) (μ-Calpain) is an intracellular Ca2+-regulated cysteine protease. Calpain-1 (pig) exhibits neuroprotective effect.
For research use only. We do not sell to patients.
- CAS No.: 689772-75-6
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Protocols
- Purity & Documentation
- References
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Publications Citing Use of MedChemExpress (MCE) Calpain-1 (pig)
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Biological Activity
Description
Chemical Information
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CAS No. 689772-75-6
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SMILES
[Calpain-1 (pig)]
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Synonyms
μ-Calpain
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Shipping
Shipping with dry ice.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Publications (1)
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Journal Impact Factor
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Most Recent
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Eur J Pharm Sci
Calpain inhibition preserves myofilament integrity and prevents vandetanib-induced cardiac dysfunction. [Abstract]2026 May 1:220:107490. PMID: 41765115
Protocols
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Ca2+ Staining Technique
Ca2+ staining is an experimental technique that utilizes specific fluorescent probes (such as Fluo-4 AM, Fura-2, etc.) to qualitatively or quantitatively detect dynamic changes in intracellular Ca2+ concentrations; this is achieved by monitoring the changes in fluorescent signals generated when these probes bind to free intracellular calcium ions. The underlying principle relies primarily on the presence of chelating groups within the probe's molecular structure that possess high affinity for calcium ions.
Purity & Documentation
References
[1]. Shinkai-Ouchi F, et, al. Predictions of Cleavability of Calpain Proteolysis by Quantitative Structure-Activity Relationship Analysis Using Newly Determined Cleavage Sites and Catalytic Efficiencies of an Oligopeptide Array. Mol Cell Proteomics. 2016 Apr;15(4):1262-80. [Content Brief]
[2]. Baudry M, et, al. Calpain-1 and Calpain-2: The Yin and Yang of Synaptic Plasticity and Neurodegeneration. Trends Neurosci. 2016 Apr;39(4):235-245. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Calpain-1 (pig) Related Classifications
HY-E70197 Related Classifications
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