1045792-66-2
1045792-66-2
Chemical Structure
CAY10603
Synonym(s): BML-281
- CAS No.: 1045792-66-2
- Formula:C22H30N4O6
- Molecular Weight:446.50
IUPAC Name: tert-butyl (4-(3-((7-(hydroxyamino)-7-oxoheptyl)carbamoyl)isoxazol-5-yl)phenyl)carbamate
InChIKey: WWGBHDIHIVGYLZ-UHFFFAOYSA-N
SMILES: O=C(OC(C)(C)C)NC1=CC=C(C2=CC(C(NCCCCCCC(NO)=O)=O)=NO2)C=C1
Biological Activity: CAY10603 (BML-281) is a potent and selective HDAC6 inhibitor, with an IC50 of 2 pM; CAY10603 (BML-281) also inhibits HDAC1, HDAC2, HDAC3, HDAC8, HDAC10, with IC50s of 271, 252, 0.42, 6851, 90.7 nM.
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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CAY10603 | 99.76% | CAY10603 (BML-281) is a potent and selective HDAC6 inhibitor, with an IC50 of 2 pM; CAY10603 (BML-281) also inhibits HDAC1, HDAC2, HDAC3, HDAC8, HDAC10, with IC50s of 271, 252, 0.42, 6851, 90.7 nM. | ||||||||||||||||||||
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CAY10603 (Standard) | ≥98% | CAY10603 (Standard) is the analytical standard of CAY10603. This product is intended for research and analytical applications. CAY10603 (BML-281) is a potent and selective HDAC6 inhibitor, with an IC50 of 2 pM; CAY10603 (BML-281) also inhibits HDAC1, HDAC2, HDAC3, HDAC8, HDAC10, with IC50s of 271, 252, 0.42, 6851, 90.7 nM. | ||||||||||||||||||||
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Keywords
