2836342-69-7
2836342-69-7
Chemical Structure
Akt3 degrader 1
- CAS No.: 2836342-69-7
- Formula:C53H72N8O4
- Molecular Weight:885.19
IUPAC Name: 2,6-di-tert-butylaniline
InChIKey: KLSALARRZCZNDM-UHFFFAOYSA-N
SMILES: COC1=C(C=CC(N2CCN(CC2)CCCCCCCCCCCCNC(CC34CC5CC(C4)CC(C3)C5)=O)=C1)NC6=NC=C7C(C)=CC(N(C7=N6)C8=CC=CC(NC(C9CC9)=O)=C8)=O
Biological Activity: Akt3 degrader 1 is an orally active selective Akt3 degrader with a DC50 of 13 nM. Akt3 degrader 1 binds to the PH domain of Akt3 to trigger proteasome-mediated degradation, with minimal effects on Akt1/Akt2. Akt3 degrader 1 inhibits cancer cell growth. Akt3 degrader 1 can be used for the research of non-small cell lung cancer[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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Akt3 degrader 1 | 95.10% | Akt3 degrader 1 is an orally active selective Akt3 degrader with a DC50 of 13 nM. Akt3 degrader 1 binds to the PH domain of Akt3 to trigger proteasome-mediated degradation, with minimal effects on Akt1/Akt2. Akt3 degrader 1 inhibits cancer cell growth. Akt3 degrader 1 can be used for the research of non-small cell lung cancer. | ||||||||||||||||||||
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