529-59-9
Chemical Structure
Genistin
Synonym(s): Genistine; Genistoside; Genistein 7-O-β-D-glucopyranoside
- CAS No.: 529-59-9
- Formula:C21H20O10
- Molecular Weight:432.38
IUPAC Name: 5-hydroxy-3-(4-hydroxyphenyl)-7-(((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)tetrahydro-2H-pyran-2-yl)oxy)-4H-chromen-4-one
InChIKey: ZCOLJUOHXJRHDI-CMWLGVBASA-N
SMILES: O=C(C(C1=CC=C(O)C=C1)=COC2=CC(O[C@@H]([C@@H]([C@@H](O)[C@@H]3O)O)O[C@@H]3CO)=C4)C2=C4O
Biological Activity: Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway[1][2][3].
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Genistin | 98.40% | Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway. | ||||||||||||||||||||
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Genistin (Standard) | ≥98% | Genistin (Standard) is the analytical standard of Genistin. This product is intended for research and analytical applications. Genistin (Genistine), an isoflavone belonging to the phytoestrogen family, is a potent anti-adipogenic and anti-lipogenic agent. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway. | ||||||||||||||||||||
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References
- [1]. Choi YR, et al. Genistin: A Novel Potent Anti-Adipogenic and Anti-Lipogenic Agent. Molecules. 2020;25(9):2042. Published 2020 Apr 27. [Content Brief]
- [2]. Liang Y, et al. A Comprehensive Screening and Identification of Genistin Metabolites in Rats Based on Multiple Metabolite Templates Combined with UHPLC-HRMS Analysis. Molecules. 2018;23(8):1862. Published 2018 Jul 26. [Content Brief]
- [3]. Hwang ST, et al. Genistin attenuates cellular growth and promotes apoptotic cell death breast cancer cells through modulation of ERalpha signaling pathway [published online ahead of print, 2020 Oct 16]. Life Sci. 2020;263:118594. [Content Brief]
