69762-85-2
69762-85-2
Chemical Structure
W-7 isomer hydrochloride
- No. CAS: 69762-85-2
- Formula:C16H22Cl2N2O2S
- Molecular Weight:377.33
IUPAC Name: N-(6-aminohexyl)-5-chloronaphthalene-2-sulfonamide hydrochloride
InChIKey: FGWDLQXTCSKXSK-UHFFFAOYSA-N
SMILES: O=S(C1=CC=C2C(Cl)=CC=CC2=C1)(NCCCCCCN)=O.[H]Cl
Biological Activity: W-7 isomer hydrochloride is an isomer of W-7 hydrochloride (HY-100912). W-7 hydrochloride is a selective calmodulin antagonist[1].
| Referencia número | Nombre del producto | Pureza | Descripciòn | Pricing | |||||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
W-7 isomer hydrochloride | 99.65% | W-7 isomer hydrochloride is an isomer of W-7 hydrochloride (HY-100912). W-7 hydrochloride is a selective calmodulin antagonist. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
W-13 hydrochloride | 99.70% | W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
W-5 hydrochloride | 99.93% | W-5 hydrochloride is a calmodulin antagonist. W-5 hydrochloride inhibits phosphodiesterase activation with an IC50 value of 240 µM. W-5 hydrochloride can be used as a negative control for W-7 (HY-100912). | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
W-7 hydrochloride (Standard) | ≥98% | W-7 (hydrochloride) (Standard) is the analytical standard of W-7 (hydrochloride) (HY-100912). This product is intended for research and analytical applications. W-7 hydrochloride is a selective calmodulin antagonist. W-7 hydrochloride inhibits the Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase with IC50 values of 28 μM and 51 μM, respectively. W-7 hydrochloride induces apoptosis and has antitumor and vascular relaxing activity. W-7 hydrochloride is a blocker of Kv4.3 and can be used for research of arrhythmias. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
A-7 hydrochloride | 99.09% | A-7 hydrochloride (Ophobolin A) is a calmodulin antagonist and can be used for the research of cancer. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
H-9 Dihydrochloride | 98.98% | H-9 Dihydrochloride is a PKA (protein kinase) inhibitor. H-9 Dihydrochloride (10 μM) significantly reduces the excitatory response to 5-HT. H-9 Dihydrochloride also has a direct effect on pharyngeal activity. H-9 Dihydrochloride inhibits signal-transduction and cell growth in EGF (epidermal growth factor)-dependent epithelial cell lines. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
SC-10 | 99.59% | SC-10 is a direct activator of PKC. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Calmodulin antagonist-1 | 99.28% | Calmodulin antagonist-1 (A-5) is a calmodulin (CaM) antagonist. Calmodulin antagonist-1 inhibits calmodulin-activated Ca2+-phosphodiesterase (PDE) (IC50=66 μM). Calmodulin antagonist-1 also inhibits trypsin-treated Ca2+-PDE (IC50=560 μM) in a competitive fashion with respect to cyclic GMP. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
A-3 hydrochloride | 99.45% | A-3 hydrochloride is a potent, cell-permeable, reversible, ATP-competitive non-selective antagonist of various kinases. It against PKA (Ki=4.3 µM), casein kinase II (Ki=5.1 µM) and myosin light chain kinase (MLCK) (Ki=7.4 µM). A-3 hydrochloride also inhibits PKC and casein kinase I with Ki values of 47 µM and 80 µM, respectively. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
W-7 | 99.35% | W-7 is a selective calmodulin antagonist. W-7 inhibits the Ca2+-calmodulin-dependent phosphodiesterase and myosin light chain kinase with IC50 values of 28 μM and 51 μM, respectively. W-7 induces apoptosis and has antitumor and vascular relaxing activity. W-7 is a blocker of Kv4.3 and can be used for research of arrhythmias. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
|
|
Dansylcadaverine | 99.10% | Dansylcadaverine (Monodansyl cadaverine) is an autofluorescent compound used for the labeling of autophagic vacuoles. Dansylcadaverine, a high affinity substrate of transglutaminases, can block the receptor-mediated endocytosis of many ligands. | ||||||||||||||||||||
|
loading...
/
|
|||||||||||||||||||||||
