W-13 hydrochloride
Based on 1 Customer Validation
W-13 hydrochloride is a calmodulin antagonist. W-13 hydrochloride can inhibit Tamoxifen (HY-13757A)-resistant human breast cancer cell growth.
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- Pureté: 99.86%
- CAS No.: 88519-57-7
- Formule: C14H18Cl2N2O2S
- Masse moléculaire:349.28
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Stockage:
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Kinase Inhibitor Library
HY-L009
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Neuronal Signaling Compound Library
HY-L013
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Anti-Cancer Compound Library
HY-L025
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Anti-Breast Cancer Compound Library
HY-L074
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Serine/Threonine Kinase Inhibitor Library
HY-L164
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Anti-Drug-Resistant Compound Library
HY-L169
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Bioactive Compound Library Max
HY-L181
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MCE Bioactive Compound Library
HY-L001V
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Bioactive Compound Library
HY-L001
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Posttranslational Modification Library
HY-L226
Activité biologique
Chemical Information
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CAS No. 88519-57-7
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Appearance Solid
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Masse moléculaire 349.28
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Formule C14H18Cl2N2O2S
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Color White to off-white
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SMILES
O=S(C1=CC=C2C(Cl)=CC=CC2=C1)(NCCCCN)=O.[H]Cl
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
-20°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 125 mg/mL (357.88 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
H2O : 25 mg/mL (71.58 mM; Need ultrasonic)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Instruction de manipulation (2659 KB)
Références
[1]. Tallant EA, et, al. Calmodulin antagonists elevate the levels of 32P-labeled polyphosphoinositides in human platelets. Biochem Biophys Res Commun. 1985 Aug 30;131(1):370-7. [Content Brief]
[2]. Strobl JS, et, al. Tamoxifen-resistant human breast cancer cell growth: inhibition by thioridazine, pimozide and the calmodulin antagonist, W-13. J Pharmacol Exp Ther. 1992 Oct;263(1):186-93. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / DMSO | 1 mM | 2.8630 mL | 14.3152 mL | 28.6303 mL | 71.5758 mL |
| 5 mM | 0.5726 mL | 2.8630 mL | 5.7261 mL | 14.3152 mL | |
| 10 mM | 0.2863 mL | 1.4315 mL | 2.8630 mL | 7.1576 mL | |
| 15 mM | 0.1909 mL | 0.9543 mL | 1.9087 mL | 4.7717 mL | |
| 20 mM | 0.1432 mL | 0.7158 mL | 1.4315 mL | 3.5788 mL | |
| 25 mM | 0.1145 mL | 0.5726 mL | 1.1452 mL | 2.8630 mL | |
| 30 mM | 0.0954 mL | 0.4772 mL | 0.9543 mL | 2.3859 mL | |
| 40 mM | 0.0716 mL | 0.3579 mL | 0.7158 mL | 1.7894 mL | |
| 50 mM | 0.0573 mL | 0.2863 mL | 0.5726 mL | 1.4315 mL | |
| 60 mM | 0.0477 mL | 0.2386 mL | 0.4772 mL | 1.1929 mL | |
| DMSO | 80 mM | 0.0358 mL | 0.1789 mL | 0.3579 mL | 0.8947 mL |
| 100 mM | 0.0286 mL | 0.1432 mL | 0.2863 mL | 0.7158 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
W-13 hydrochloride Related Classifications
HY-100910 Related Classifications
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