853299-52-2
Chemical Structure
ATH686
- CAS No.: 853299-52-2
- Formula:C25H28F3N7O2
- Molecular Weight:515.53
IUPAC Name: 1-(4-((2-aminopyrimidin-4-yl)oxy)phenyl)-3-(4-((4-ethylpiperazin-1-yl)methyl)-3-(trifluoromethyl)phenyl)urea
InChIKey: VQQRBBFRJRBWPF-UHFFFAOYSA-N
SMILES: NC1=NC(OC2=CC=C(NC(NC3=CC(C(F)(F)F)=C(CN4CCN(CC)CC4)C=C3)=O)C=C2)=CC=N1
Biological Activity: ATH686 is a potent, selective and ATP-competitive FLT3 inhibitor. ATH686 target mutant FLT3 protein kinase activity and inhibit the proliferation of cells harboring FLT3 mutants via induction of apoptosis and cell cycle inhibition. ATH686 has antileukemic effects[1].
| Cat. No. | Product Name | Purity | Description | Pricing | |||||||||||||||||||
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ATH686 | 99.54% | ATH686 is a potent, selective and ATP-competitive FLT3 inhibitor. ATH686 target mutant FLT3 protein kinase activity and inhibit the proliferation of cells harboring FLT3 mutants via induction of apoptosis and cell cycle inhibition. ATH686 has antileukemic effects. | ||||||||||||||||||||
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Keywords
