Calf thymus DNA
Based on 7 publication(s) in Google Scholar
Calf thymus DNA (DNA from calf thymus) is high quality double-stranded template DNA isolated from the thymus of male and female calves. Calf thymus DNA can be used for the research of the interaction between DNA and agents.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 91080-16-9
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Speicherung:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
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Lösungsmittel & Löslichkeit
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Calf thymus DNA
More- Nat Commun. 2024 Dec 5;15(1):10599. [Abstract]
- J Med Chem. 2026 Jun 25;69(12):14492-14512. [Abstract]
- J Ethnopharmacol. 2025 Feb 11:341:119304. [Abstract]
- Pharm Res. 2026 May 27. [Abstract]
- J Transl Autoimmun. 2026 Jan 12:12:100349. [Abstract]
- chemRxiv. 2025 Dec 22.
- Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Customer Validation & Images
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ELISA
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ELISA
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ELISA
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Bio/Physico-chemical Assay
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Bio/Physico-chemical Assay
Alle DNA/RNA Synthesis Isoform-spezifische Produkte anzeigen
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Biologische Aktivität
Calf thymus DNA interacts with the antiviral drug Lamivudine that can be studied using emission, absorption, circular dichroism (CD), and viscosity techniques[2].
Note: To reduce DNA shearing, sonication or agitation should not be used. It's recommended to shake gently overnight at 0-4°C to completely dissolve the DNA.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 91080-16-9
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Appearance Solid
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Color White to light yellow
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SMILES
[Calf thymus DNA]
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Synonyms
DNA from calf thymus, Thymonucleic acid
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Structure Classification
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Initial Source
the thymus of male and female calves
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Publications (7)
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Journal Impact Factor
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Most Recent
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Nat Commun
Aberrant METTL1-mediated tRNA m7G modification alters B-cell responses in systemic autoimmunity in humans and mice. [Abstract]2024 Dec 5;15(1):10599. PMID: 39638793 -
J Med Chem
Structure-Guided Discovery of Potent, Selective, and Orally Bioavailable Werner Syndrome RecQ Helicase Inhibitors for the Treatment of Microsatellite Instability-High Tumors. [Abstract]2026 Jun 25;69(12):14492-14512. PMID: 42234810 -
J Ethnopharmacol
Investigating the mechanism of Tongfeng Qingxiao Formula for improving gouty arthritis based on the neutrophil extracellular trapping network. [Abstract]2025 Feb 11:341:119304. PMID: 39736350 -
Pharm Res
Rational Design, Optimization and Bioinformatic Analysis of Anti-PD-L1 Peptide Conjugated Mocetinostat Prodrug Nanoparticles for Predictive Cancer Chemoimmunotherapeutic Efficacy. [Abstract]2026 May 27. PMID: 42204129 -
J Transl Autoimmun
Liraglutide prevents lupus-associated diffuse alveolar hemorrhage via inhibiting lymphocyte infiltration and promoting macrophage M2 polarization. [Abstract]2026 Jan 12:12:100349. PMID: 41626528 -
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Biomed Pharmacother
Ginsenoside Rb1 mitigates acute catecholamine surge-induced myocardial injuries in part by suppressing STING-mediated macrophage activation. [Abstract]2024 Jun:175:116794. PMID: 38776673
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
RAW264.7 cells were treated with either vehicle or Rb1 at 50, 100, 200 and 400 μM in the presence or absence of 2 μg/ml ctDNA (Calf thymus DNA) stimulation. The levels of TNFα, IL6 and CCL2 in the culture supernatants collected 3 h post ctDNA stimulation were analyzed by ELISA.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
The supernatants were collected 6 h post ctDNA (Calf thymus DNA) stimulation and the production of TNFα, IL6, CCL2 and IFN-β was quantified by ELISA.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
The supernatants collected 12 h post ctDNA (Calf thymus DNA) stimulation were analyzed by ELISA to quantify the level of TNFα, IL6, CCL2 and IFN-β.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Volcano plot of DEGs from the ctDNA (Calf thymus DNA) vs Ctrl. C. Line charts categorizing DEGs (ctDNA vs Ctrl) using Mfuzz clustering.
Calf thymus DNA purchased from MedChemExpress. Usage Cited in: Biomed Pharmacother. 2024 Jun:175:116794. [Abstract]
Enriched pathways revealed by GSEA (Rb1 vs ctDNA (Calf thymus DNA)). Ctrl, vehicle-treated RAW264.7 cells; ctDNA, vehicle-treated ctDNA-stimulated RAW264.7 cells; Rb1, Rb1-treated ctDNA-stimulated RAW264.7 cells; NES normalized enrichment score.
Lösungsmittel & Löslichkeit
H2O : ≥ 1 mg/mL
* "≥" means soluble, but saturation unknown.
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Liu F, et al. Cytotoxicity of Aconitum alkaloid and its interaction with calf thymus DNA by multi-spectroscopic techniques. Sci Rep. 2017 Nov 6;7(1):14509. [Content Brief]
[2]. Shahabadi N, et, al. Interaction of calf thymus DNA with the antiviral drug Lamivudine. DNA Cell Biol. 2012 Jan;31(1):122-7. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Calf thymus DNA Related Classifications
HY-109517 Related Classifications
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