Art. -Nr.: HY-101445

Trolox

36 Cited Publications

Kundenbewertung

Based on 36 publication(s) in Google Scholar

Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

Reinheit: 99.90%
CAS. Nr.: 53188-07-1
Formel: C₁₄H₁₈O₄
Molecular Weight:250.29

Speicherung:

Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 1 year , -20°C, 6 months

Trolox Chemical Structure

CAS. Nr.: 53188-07-1

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- Cellular Effect
- In Vitro
Chemical Information
Publications (36)
Lösungsmittel & Löslichkeit
- In Vitro
- In Vivo
Protokoll
Reinheit & Dokumentation
Verweise
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

Trolox is an analogue of vitamin E with a powerful antioxidant effect. Trolox is also a powerful inhibitor of membrane damage^[1]^[2].

Cellular Effect

Cell Line	Type	Value	Description	References
A549	GI₅₀	>100 μM Compound: 2a	Antiproliferative activity against human A549 cells after 48 hrs by SRB assay Antiproliferative activity against human A549 cells after 48 hrs by SRB assay	[PMID: 29129514]
Erythrocyte	IC₅₀	101 μM Compound: trolox	Antioxidant activity assessed as inhibition of AAPH-induced hemolysis in rat RBC after 3 hrs Antioxidant activity assessed as inhibition of AAPH-induced hemolysis in rat RBC after 3 hrs	[PMID: 12828473]
HBL-100	GI₅₀	>100 μM Compound: 2a	Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay Antiproliferative activity against human HBL100 cells after 48 hrs by SRB assay	[PMID: 29129514]
HeLa	GI₅₀	>100 μM Compound: 2a	Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay Antiproliferative activity against human HeLa cells after 48 hrs by SRB assay	[PMID: 29129514]
HepG2	IC₅₀	>300 μM Compound: TroH	Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human HepG2 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 27344490]
HL-60	IC₅₀	0.3 μg/mL Compound: Trolox	Antioxidant activity in PMA-stimulated Homo sapiens (human) HL60 cells assessed as inhibition of intracellular ROS generation incubated for 30 min prior to PMA stimulation measured after 30 min by DCFH-DA assay Antioxidant activity in PMA-stimulated Homo sapiens (human) HL60 cells assessed as inhibition of intracellular ROS generation incubated for 30 min prior to PMA stimulation measured after 30 min by DCFH-DA assay	10.1007/s00044-011-9882-z
HL-60	IC₅₀	1.4 μM Compound: Trolox	Inhibition of PMA induced ROS generation in human HL60 cells assessed as inhibition of ROA mediated oxidation of DCFH Inhibition of PMA induced ROS generation in human HL60 cells assessed as inhibition of ROA mediated oxidation of DCFH	[PMID: 23547843]
HL-60	IC₅₀	3.6 μM Compound: trolox	Antioxidant activity in human HL60 cells assessed as inhibition of TPA-stimulated hydrogen peroxide induced DCFH-DA oxidation by fluorometric microplate assay Antioxidant activity in human HL60 cells assessed as inhibition of TPA-stimulated hydrogen peroxide induced DCFH-DA oxidation by fluorometric microplate assay	[PMID: 16562834]
MCF7	IC₅₀	>300 μM Compound: TroH	Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MCF7 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 27344490]
MCF7	IC₅₀	1461 μM Compound: 14	Compound was tested for antiproliferative activity against human breast cancer cell line MCF-7 in MTT assay Compound was tested for antiproliferative activity against human breast cancer cell line MCF-7 in MTT assay	[PMID: 9873556]
Melan-a	IC₅₀	>300 μM Compound: 2	Depigmentation activity in mouse Melan-a cells assessed as inhibition of melanin formation after 4 days Depigmentation activity in mouse Melan-a cells assessed as inhibition of melanin formation after 4 days	[PMID: 22071299]
Melan-a	IC₅₀	300 μM Compound: 2	Cytotoxicity against mouse Melan-a cells by modified crystal voilet assay Cytotoxicity against mouse Melan-a cells by modified crystal voilet assay	[PMID: 22071299]
MT4	IC₅₀	200 μM Compound: TroH	Cytotoxicity against human MT4 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human MT4 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 27344490]
NRK-52E	EC₅₀	1.9 μM Compound: Trolox	Cytoprotective activity against LPS-induced NRK-52E cells assessed as reduction in cell death measured every 5 min for 72 hrs by xCELLigence based RTCA analysis Cytoprotective activity against LPS-induced NRK-52E cells assessed as reduction in cell death measured every 5 min for 72 hrs by xCELLigence based RTCA analysis	[PMID: 32141747]
PC-12	IC₅₀	20 μM Compound: Trolox	Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced ROS production after 1 hr by DCFH-DA staining-based fluorometric analysis	[PMID: 23751098]
PC-12	IC₅₀	20 μM Compound: Trolox	Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced reactive oxygen species formation after 1 hr by DCFH-DA dye-based fluorometric analysis Antioxidant activity in rat PC12 cells assessed as inhibition of Fe2+-induced reactive oxygen species formation after 1 hr by DCFH-DA dye-based fluorometric analysis	[PMID: 26447940]
RAW264.7	IC₅₀	30 μM Compound: Trx	Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced ROS production measured after 4 hrs by H2DCFDA-AM probe based fluorescence assay Anti-inflammatory activity in mouse RAW264.7 cells assessed as inhibition of LPS-induced ROS production measured after 4 hrs by H2DCFDA-AM probe based fluorescence assay	[PMID: 29275229]
RPMI-8226	IC₅₀	>300 μM Compound: TroH	Cytotoxicity against human RPMI8226 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human RPMI8226 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 27344490]
SH-SY5Y	IC₅₀	49.55 μM Compound: Trolox	Antioxidant activity against tert-butyl hydroperoxide-induced ROS evoked cell death in human SH-SY5Y cells Antioxidant activity against tert-butyl hydroperoxide-induced ROS evoked cell death in human SH-SY5Y cells	[PMID: 18605718]
SH-SY5Y	IC₅₀	82.3 μM Compound: Trolox	Antioxidant activity in human SH-SY5Y cells assessed as inhibition of H2O2-induced DCFH oxidation measured after 1 hr by DCFH-DA dye based fluorescence assay Antioxidant activity in human SH-SY5Y cells assessed as inhibition of H2O2-induced DCFH oxidation measured after 1 hr by DCFH-DA dye based fluorescence assay	[PMID: 27541262]
SW1573	GI₅₀	>100 μM Compound: 2a	Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay Antiproliferative activity against human SW1573 cells after 48 hrs by SRB assay	[PMID: 29129514]
T47D	GI₅₀	>100 μM Compound: 2a	Antiproliferative activity against human T47D cells after 48 hrs by SRB assay Antiproliferative activity against human T47D cells after 48 hrs by SRB assay	[PMID: 29129514]
U-937	IC₅₀	300 μM Compound: TroH	Cytotoxicity against human U937 cells assessed as reduction in cell viability after 72 hrs by MTT assay Cytotoxicity against human U937 cells assessed as reduction in cell viability after 72 hrs by MTT assay	[PMID: 27344490]
WiDr	GI₅₀	>100 μM Compound: 2a	Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay Antiproliferative activity against human WiDr cells after 48 hrs by SRB assay	[PMID: 29129514]

In Vitro

Trolox has shown to protect mammalian cells from oxidative damage. Trolox is effective in preventing myocyte necrosis in cell culture studies and in a canine model of two hours of left anterior descending coronary artery (LAD) occlusion followed by four hours of reperfusion^[1].
Trolox could prevent oxidative stress-induced apoptosis in thymocytes. Pre- or post-treatment of cells with Trolox reduced H₂O₂-induced DNA fragmentation to control levels and below. ^[2].
Trolox is a hydrophilic analog of alpha-tocopherol and reported to scavenge peroxyl radicals better than vitamin E in sodium dodecyl sulfate micelles and in liposomes. Trolox prolongs substantially the survival of human ventricular myocytes and hepatocyte against oxyradicals generated with xanthine oxidase plus hypoxanthine, and prevented lysis of red cells exposed to an azo-initiator^[3].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 53188-07-1
Appearance Solid
Molecular Weight 250.29
Formel C₁₄H₁₈O₄
Color Off-white to gray
SMILES

O=C(C1(C)CCC2=C(C)C(O)=C(C)C(C)=C2O1)O
Versand

Room temperature in continental US; may vary elsewhere.

Speicherung

Powder	-20°C	3 years
	4°C	2 years
In solvent	-80°C	1 year
	-20°C	6 months

Publications (36)

All Cell Proliferation/Viability AssayBio/Physico-chemical AssayFlow CytometryWB

Sort by:

Journal Impact Factor

Nature

STING agonist-based ER-targeting molecules boost antigen cross-presentation. [Abstract]

2025 May;641(8061):202-210. PMID: 40140567
Nature

Emergence of large-scale cell death through ferroptotic trigger waves. [Abstract]

2024 Jul;631(8021):654-662. PMID: 38987590
Nat Commun

Observation of structural switch in nascent SAM-VI riboswitch during transcription at single-nucleotide and single-molecule resolution. [Abstract]

2023 Apr 22;14(1):2320. PMID: 37087479
Adv Sci (Weinh)

Novel Swelling-Lytic Cell Death Triggered by Cargo-Free Ionizable Lipid Nanoparticles. [Abstract]

2025 Aug 7:e09208. PMID: 40776529

Trolox purchased from MedChemExpress. Usage Cited in: Adv Sci (Weinh). 2025 Aug 7:e09208. [Abstract]

Trolox (100 µM), a hydrophilic analogue of VE with potent antioxidant effect, was used as a control of VE. After a short incubation time of 6 h, cathepsin inhibitors (CA‐074, Pep‐A, and E‐64), Ca²⁺ chelator, and cellular ROS scavengers (NAC, VC, and Trolox) displayed a delayed effect of ipLNP cytotoxicity.
Adv Sci (Weinh)

Aloperine Suppresses Cancer Progression by Interacting with VPS4A to Inhibit Autophagosome-lysosome Fusion in NSCLC. [Abstract]

2024 Aug;11(31):e2308307. PMID: 39166458
J Nanobiotechnology

Single-cell multi-omics analysis reveals the mechanism of action of a novel antioxidant polyphenol nanoparticle loaded with STAT3 agonist in mediating cardiomyocyte ferroptosis to ameliorate age-related heart failure. [Abstract]

2025 Mar 29;23(1):258. PMID: 40158134
Int J Biol Sci

Timosaponin AIII promotes non-small-cell lung cancer ferroptosis through targeting and facilitating HSP90 mediated GPX4 ubiquitination and degradation. [Abstract]

2023 Feb 27;19(5):1471-1489. PMID: 37056925
Food Chem

Optimization of multi-enzyme coupled debittering process: Effect on bitterness and bioactive components of Shatianyu (Citrus grandis L. Osbeck) whole fruit powder. [Abstract]

2026 Mar 28:515:149066. PMID: 41990492
Cell Death Dis

Utidelone inhibits growth of colorectal cancer cells through ROS/JNK signaling pathway. [Abstract]

2021 Apr 1;12(4):338. PMID: 33795638
Proc Natl Acad Sci U S A

Divergent molecular assembly and catalytic mechanisms between bacterial and archaeal RNase P in pre-tRNA cleavage. [Abstract]

2024 Oct 22;121(43):e2407579121. PMID: 39413135
EMBO J

Stearate-derived very long-chain fatty acids are indispensable to tumor growth. [Abstract]

2023 Jan 16;42(2):e111268. PMID: 36408830
Cell Death Discov

Metabolic interplay between exogenous cystine and glutamine dependence in triple-negative breast cancer. [Abstract]

2025 Oct 6;11(1):430. PMID: 41053011

Trolox purchased from MedChemExpress. Usage Cited in: Cell Death Discov. 2025 Oct 6;11(1):430. [Abstract]

Trolox (5 µM) also rescued TNBC cells from cystine deprivation-induced cell death by reducing ROS levels. Representative images of Hs578Ts(i)₈ and SUM159 cells treated with Trolox and/or glutamine deprivation under cystine-deprived conditions.
Cell Death Discov

A novel SRSF3 inhibitor, SFI003, exerts anticancer activity against colorectal cancer by modulating the SRSF3/DHCR24/ROS axis. [Abstract]

2022 May 2;8(1):238. PMID: 35501301
Cell Rep

PARP-inhibition reprograms macrophages toward an anti-tumor phenotype. [Abstract]

2022 Oct 11;41(2):111462. PMID: 36223740

Trolox purchased from MedChemExpress. Usage Cited in: Cell Rep. 2022 Oct 11;41(2):111462. [Abstract]

With an alternative ROS scavenger, the vitamin E analog Trolox, Olaparib-induced ROS production was similarly suppressed
Cell Rep

Early-life vitamin B12 orchestrates lipid peroxidation to ensure reproductive success via SBP-1/SREBP1 in Caenorhabditis elegans. [Abstract]

2022 Sep 20;40(12):111381. PMID: 36130518
Cell Biosci

Hinokitiol-iron complex is a ferroptosis inducer to inhibit triple-negative breast tumor growth. [Abstract]

2023 May 13;13(1):87. PMID: 37179385
Microchem J

2026 Feb 9.
Int J Mol Sci

NEDD4L-Mediated Ubiquitination of GPX4 Exacerbates Doxorubicin-Induced Cardiotoxicity. [Abstract]

2025 Aug 23;26(17):8201. PMID: 40943126
PLoS Pathog

Chlamydial protease-like activity factor targets SLC7A11 for degradation to induce ferroptosis and facilitate progeny releases. [Abstract]

2025 Apr 8;21(4):e1013060. PMID: 40198689
Cancers (Basel)

Synthesis and Biological Evaluation of a Caffeic Acid Phenethyl Ester Derivatives as Anti-Hepatocellular Carcinoma Agents via Inhibition of Mitochondrial Respiration and Disruption of Cellular Metabolism. [Abstract]

2025 Dec 27;18(1):92. PMID: 41514605
Nanomaterials

Effect of Fullerenol C60(OH)24 on Viability and Phagocytic Activity of Human Neutrophils. [Abstract]

2026 Mar 27;16(7):405. PMID: 41972621
ACS Omega

Identification of Phialomustin‑B (PHL-B) as a Novel Natural TRPA1 Channel Inhibitor. [Abstract]

2025 Aug 21;10(34):39192-39202. PMID: 40918390
Exp Gerontol

Endoplasmic reticulum stress-induced necroptosis promotes cochlear inflammation: Implications for age-related hearing loss. [Abstract]

2024 May:189:112401. PMID: 38490286
Transl Oncol

Exploring the role of disulfidptosis-related signatures in immune microenvironment, prognosis and therapeutic strategies of cervical cancer. [Abstract]

2024 Jun:44:101938. PMID: 38492499
Nanotoxicology

Iron oxide nanoparticles cause surface coating- and core chemistry-dependent endothelial cell ferroptosis. [Abstract]

2022 Nov-Dec;16(9-10):829-843. PMID: 36660964
Neurotox Res

Duloxetine-Induced Neural Cell Death and Promoted Neurite Outgrowth in N2a Cells. [Abstract]

2020 Dec;38(4):859-870. PMID: 32415528
Life Sci Alliance

Tanshinone functions as a coenzyme that confers gain of function of NQO1 to suppress ferroptosis. [Abstract]

2022 Nov 1;6(1):e202201667. PMID: 36319062
Fitoterapia

New sesquiterpenoids with neuroprotective effects in vitro and in vivo from the Picrasma chinensis. [Abstract]

2024 Jun:175:105908. PMID: 38479621
bioRxiv

2026 May 21.
Res Sq

2026 Jan 9.
Res Sq

2025 Feb 16.
Sri Lanka Journal of Indigenous Medicine

2024; 09(01): 820-824
Med Rev (2021)

MST1 interactomes profiling across cell death in esophageal squamous cell carcinoma. [Abstract]

2024 Jun 14;4(6):531-543. PMID: 39664081
bioRxiv

2023 Dec 5.
bioRxiv

2023 Dec 20.
Oxid Med Cell Longev

Redox Biology of Infection and Consequent Disease. [Abstract]

2020 Jan 27;2020:5829521. PMID: 32089773

Trolox purchased from MedChemExpress. Usage Cited in: Oxid Med Cell Longev. 2020 Jan 27;2020:5829521. [Abstract]

The effects of Trolox on the expression of Nrf2 and its downstream targets. MDBK cells in 60 mm dishes pretreated with Trolox (1 mM) or DMSO control for 1 h are exposed to tBHP in the presence of Trolox or DMSO control for 2 h; the cell lysates are prepared for Western blots to detect the expression of Nrf2 and HO-1.

Lösungsmittel & Löslichkeit

In Vitro:

DMSO : 175 mg/mL (699.19 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

H₂O : < 0.1 mg/mL (insoluble)

View the Complete Stock Solution Preparation Table

Preparing Stock Solutions

View the Complete Stock Solution Preparation Table

Concentration Solvent Mass

1 mg

5 mg

10 mg

Concentration

Solvent

Mass

1 mM

3.9954 mL

19.9768 mL

39.9537 mL

5 mM

0.7991 mL

3.9954 mL

7.9907 mL

10 mM

0.3995 mL

1.9977 mL

3.9954 mL

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

In Vivo:

Select the appropriate dissolution method based on your experimental animal and administration route.

Stock Solution Working Solution

For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.

Protocol 1

Add each solvent one by one: 10% DMSO 40% PEG300 5% Tween-80 45% Saline

Solubility: ≥ 2.08 mg/mL (8.31 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 400 μL PEG300, and mix evenly; then add 50 μL Tween-80 and mix evenly; then add 450 μL Saline to adjust the volume to 1 mL.

Protocol 2

Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)

Solubility: ≥ 2.08 mg/mL (8.31 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown).

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.

Protocol 3

Add each solvent one by one: 10% DMSO 90% Corn Oil

Solubility: ≥ 2.08 mg/mL (8.31 mM); Clear solution

This protocol yields a clear solution of ≥ 2.08 mg/mL (saturation unknown). If the continuous dosing period exceeds half a month, please choose this protocol carefully.

Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (20.8 mg/mL) to 900 μL Corn oil, and mix evenly.

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage Dosage
mg/kg
Animal Weight (Per Animal) Animal Weight (Per Animal)
g
Dosing Volume (Per Animal) Dosing Volume (Per Animal)
μL
Number of Animals Number of Animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Please enter your animal formula composition:

%
DMSO +

Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
%
+
+
%
Tween-80 + +
%
Saline +

The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).

Working solution concentration: 0.22 mg/mL

Protokoll

Cell Assay^[1]

Thymocytes are treated with Trolox (10 mM) before, during, or after 10 min exposure to 10 μM H₂O₂. Trolox incubations that are conducted before or after H₂O₂ exposures are performed in TCM. Trolox treatments that are administered concurrently with H₂O₂ are performed in PBS with ferrous sulfate^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (275 KB)
SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Mickle DA, et al. Myocardial salvage with trolox and ascorbic acid for an acute evolving infarction. Ann Thorac Surg. 1989 Apr;47(4):553-7. [Content Brief]

[2]. Forrest VJ, et al. Oxidative stress-induced apoptosis prevented by Trolox. Free Radic Biol Med. 1994 Jun;16(6):675-84. [Content Brief]

[3]. Wu TW, et al. The cytoprotective effect of Trolox demonstrated with three types of human cells. Biochem Cell Biol. 1990 Oct;68(10):1189-94. [Content Brief]

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
DMSO	1 mM	3.9954 mL	19.9768 mL	39.9537 mL	99.8841 mL
	5 mM	0.7991 mL	3.9954 mL	7.9907 mL	19.9768 mL
	10 mM	0.3995 mL	1.9977 mL	3.9954 mL	9.9884 mL
	15 mM	0.2664 mL	1.3318 mL	2.6636 mL	6.6589 mL
	20 mM	0.1998 mL	0.9988 mL	1.9977 mL	4.9942 mL
	25 mM	0.1598 mL	0.7991 mL	1.5981 mL	3.9954 mL
	30 mM	0.1332 mL	0.6659 mL	1.3318 mL	3.3295 mL
	40 mM	0.0999 mL	0.4994 mL	0.9988 mL	2.4971 mL
	50 mM	0.0799 mL	0.3995 mL	0.7991 mL	1.9977 mL
	60 mM	0.0666 mL	0.3329 mL	0.6659 mL	1.6647 mL
	80 mM	0.0499 mL	0.2497 mL	0.4994 mL	1.2486 mL
	100 mM	0.0400 mL	0.1998 mL	0.3995 mL	0.9988 mL

Keywords

Trolox

36 Cited Publications

100 mg Angebot einholen

Subscribe to the

MedChemExpress

Newsletter

Produktname:
Art. -Nr.:
Menge:
MCE Japan Authorized Agent:

Produktname:
CAS. Nr.:
Species:
Reinheit:
Menge:

Trolox

Apoptosis Compound Library

Immunology/Inflammation Compound Library

Metabolism/Protease Compound Library

NF-κB Signaling Compound Library

Anti-Cancer Compound Library

Anti-Aging Compound Library

Antioxidant Compound Library

Oxygen Sensing Compound Library

Ferroptosis Compound Library

Human Metabolite Library

Anti-Aging Natural Product Library

Cell Death Library

Radioprotector Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Anti-Fibrosis Compound Library

Vitamin Compound Library

Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Chinese Baijiu Compound Library

Lactylation Compound Library

3D Diverse Fragment Library

Publications Citing Use of MedChemExpress (MCE) Trolox

Biologische Aktivität

Chemical Information

Publications (36)

Lösungsmittel & Löslichkeit

Protokoll

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Trolox

Apoptosis Compound Library

Immunology/Inflammation Compound Library

Metabolism/Protease Compound Library

NF-κB Signaling Compound Library

Anti-Cancer Compound Library

Anti-Aging Compound Library

Antioxidant Compound Library

Oxygen Sensing Compound Library

Ferroptosis Compound Library

Human Metabolite Library

Anti-Aging Natural Product Library

Cell Death Library

Radioprotector Library

Bioactive Compound Library Max

MCE Bioactive Compound Library

Bioactive Compound Library

Anti-Fibrosis Compound Library

Vitamin Compound Library

Non-Alcoholic Fatty Liver Disease (NAFLD) Compound Library

High-Throughput Bioactive Compound Library

Mass Spectrometry Human Metabolite Library

Chinese Baijiu Compound Library

Lactylation Compound Library

3D Diverse Fragment Library

Publications Citing Use of MedChemExpress (MCE) Trolox

Biologische Aktivität

Chemical Information

Publications (36)

Lösungsmittel & Löslichkeit

Protokoll

Reinheit & Dokumentation

Verweise

Help & FAQs

Complete Stock Solution Preparation Table

Trolox Related Classifications

HY-101445 Related Classifications