AKTide-2T
AKTide-2T is an excellent in vitro substrate for AKT and shows competitive inhibition of histone H2B phosphorylation with a Ki of 12 nM. AKTide-2T mimics the optimal phosphorylation sequence of Akt and is an inhibitory peptide with the wildtype AKTide lacking Thr in the S22 position.
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- CAS. Nr.: 324029-01-8
- Formel: C74H114N28O20
- Molecular Weight:1715.87
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Chemical Information
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CAS. Nr. 324029-01-8
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Molecular Weight 1715.87
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Formel C74H114N28O20
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Sequence
Ala-Arg-Lys-Arg-Glu-Arg-Thr-Tyr-Ser-Phe-Gly-His-His-Ala
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Sequence Shortening
ARKRERTYSFGHHA
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. T Obata,et al. Peptide and protein library screening defines optimal substrate motifs for AKT/PKB. J Biol Chem. 2000 Nov 17;275(46):36108-15. [Content Brief]
[2]. Madhavi J Rane, et al. Heat shock protein 27 controls apoptosis by regulating Akt activation. J Biol Chem. 2003 Jul 25;278(30):27828-35. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
AKTide-2T Related Classifications
HY-P1115 Related Classifications
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