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Art. -Nr.: HY-175609

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Apoptosis inducer 42

Apoptosis inducer 42 is an apoptosis inducer. Apoptosis inducer 42 activates late apoptosis and inhibits IL-6 secretion. Apoptosis inducer 42 shows high cytotoxicity towards cancer cells. Apoptosis inducer 42 can be used for cancer research, such as colon cancer.

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CAS. Nr.: 66685-93-6
Formel: C₁₁H₁₃OPS
Molecular Weight:224.26

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (269 KB)

Apoptosis inducer 42 Chemical Structure

CAS. Nr.: 66685-93-6

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

IL-6

Alle Interleukin Related Isoform-spezifische Produkte anzeigen :

In Vitro

Apoptosis inducer 42 (Compound 11) inhibits SW480, SW620, PC3f, HCT116 and HaCaT cells growth with IC₅₀ values of 5.1, 6.3,6.0, 4.4 and 14.2 μM, respectively^[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) reduces the amount of live cells in SW480, SW620, PC3f and HCT116 cells^[1].
Apoptosis inducer 42 (4.4-6.3 μM, 72 h) activates late apoptosis and inhibits IL-6 secretion in SW480, SW620, PC3f and HCT116 cells^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Apoptosis Analysis^[1]

Cell Line:

SW480, SW620, PC3f and HCT116 cells
Concentration:

5.1 μM in SW480, 6.3 μM in SW620, 6.0 μM in PC3f, 4.4 μM in HCT116 cells
Incubation Time:

72 h
Result:

Activated >80% late apoptosis.

Chemical Information

CAS. Nr. 66685-93-6
Molecular Weight 224.26
Formel C₁₁H₁₃OPS
SMILES

O=C1CCP(C2=CC=CC=C2)(CC1)=S
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (269 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Łastawiecka E, et al. Design, synthesis and bioactivity evaluation of phosphinanes as potential anticancer agents. Sci Rep. 2025 Aug 2;15(1):28229. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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