Atelopidtoxin
Atelopidtoxin (zetekitoxin) is a toxin (LD50=0.016 mg/kg for mice), which can be isolated from Panamanian frog Atelopus zeteki. Atelopidtoxin causes hypotension and ventricular fibrillation in rabbits. Atelopidtoxin an inhibitor for sodium channel.
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- CAS. Nr.: 9061-57-8
- Formel: C16H24N8O12S
- Molecular Weight:552.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Beschreibung
Chemical Information
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CAS. Nr. 9061-57-8
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Molecular Weight 552.47
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Formel C16H24N8O12S
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SMILES
OC1([C@@]23[C@@]4([H])N(CN(C([C@@]4([H])N=C(N3C[C@]15C[C@](N(C(O5)=O)O)([H])[C@@H](CO)COS(=O)(O)=O)N)=O)O)C(N)=N2)O
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Structure Classification
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Initial Source
Panamanian frog, Atelopus zeteki
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
[1]. Yotsu-Yamashita M, et al. The structure of zetekitoxin AB, a saxitoxin analog from the Panamanian golden frog Atelopus zeteki: a potent sodium-channel blocker. Proc Natl Acad Sci U S A. 2004 Mar 30;101(13):4346-51. [Content Brief]
[2]. Shindelman J, et al., Atelopidtoxin from the Panamanian frog, Atelopus zeteki. Toxicon. 1969 Dec;7(4):315-9. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)