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Brentuximab

(Synonyms: CAC-10)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Brentuximab (CAC-10) is a chimeric antibody targeting CD30. Brentuximab is conjugated with Monomethyl auristatin E (MMAE) (HY-15162) to form the antibody-drug conjugate Brentuximab vedotin (HY-P99107A). Brentuximab can be used for the research of cancer, such as lymphoma.

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  • Reinheit: 99.64%
  • CAS. Nr.: 2088770-90-3
  • Molecular Weight:145.48 kDa
  • Speicherung:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Brentuximab
  • Experimental Validation Results for Brentuximab
  • Experimental Validation Results for Brentuximab
  • Brentuximab Chemical Structure
    Brentuximab Chemical Structure
CAS. Nr.: 2088770-90-3
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized CD30/TNFRSF8 Protein, Human can bind Brentuximab. The EC50 for this effect is 6.007 ng/mL.

  • 1/16

    Flow cytometric analysis of 1X106 Jurkat cells label Brentuximab (HY-P99151, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1(E356D/M358L) kappa (HY-P990100, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).

  • Brentuximab Chemical Structure
    1/16
  • Brentuximab
  • Human IgG1 kappa
  • Immobilized CD30/TNFRSF8 Protein, Human can bind Brentuximab. The EC50 for this effect is 6.007 ng/mL.
  • Flow cytometric analysis of 1X106 Jurkat cells label Brentuximab (HY-P99151, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Alexa Fluor 488-conjugated AffiniPure Goat Anti-Human IgG H&L (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG1(E356D/M358L) kappa (HY-P990100, blue) was used as the isotype control, cells without incubation with primary antibody were used as the unlabeled control (black).