CP-220629
CP-220629 is a potent inhibitor of PDE4, with the IC50 of 0.44 μM. CP-220629 is efficacious in the guinea pig aerosolized antigen induced airway obstruction assay (ED50 2.0 mg/kg).
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- CAS. Nr.: 162141-96-0
- Formel: C20H25N3O
- Molecular Weight:323.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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PDE4 0.44 μM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| U-937 | EC50 |
0.33 μM
Compound: 22
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Arbitary maximal response for cAMP elevation from baseline level was evaluated in Human U-937 cells
Arbitary maximal response for cAMP elevation from baseline level was evaluated in Human U-937 cells
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[PMID: 9632360] |
Chemical Information
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CAS. Nr. 162141-96-0
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Molecular Weight 323.43
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Formel C20H25N3O
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SMILES
O=C1C(N(C2CCCC2)N=C3CC)=C3CCN1C4=CC=CC=C4C
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
CP-220629 Related Classifications
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