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Art. -Nr.: HY-19612

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DDP-38003

1 Cited Publications

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Based on 1 publication(s) in Google Scholar

DDP-38003 (Compound 15) is an orally active KDM1A/LSD1 inhibitor with an IC₅₀ value of 84 nM. DDP-38003 exhibits anticancer activity against promyelocytic leukemia.

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CAS. Nr.: 1831167-97-5
Formel: C₂₁H₂₆N₄O
Molecular Weight:350.46

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

DDP-38003 Chemical Structure

CAS. Nr.: 1831167-97-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Publications (1)
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Biologische Aktivität

Beschreibung

DDP-38003 (Compound 15) is an orally active KDM1A/LSD1 inhibitor with an IC₅₀ value of 84 nM. DDP-38003 exhibits anticancer activity against promyelocytic leukemia^[1].

IC₅₀ & Target^[1]

KDM1/LSD1

84 nM (IC₅₀)

Alle Histone Demethylase Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 1831167-97-5
Molecular Weight 350.46
Formel C₂₁H₂₆N₄O
SMILES

O=C(NC1=CC=C([C@@H]2C[C@H]2N)C=C1)C(C=C3)=CC=C3N4CCN(C)CC4
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Publications (1)

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Clin Exp Med

Corin: a dual inhibitor for KDM1A/HDAC1, suppresses hepatocellular carcinoma by triggering cuproptosis. [Abstract]

2025 Nov 25;26(1):33. PMID: 41286164

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Vianello P, et al. Discovery of a Novel Inhibitor of Histone Lysine-Specific Demethylase 1A (KDM1A/LSD1) as Orally Active Antitumor Agent. J Med Chem. 2016 Feb 25;59(4):1501-17. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

DDP-38003

1 Cited Publications

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Biologische Aktivität
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- IC₅₀ & Target
Chemical Information
Publications (1)
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DDP-38003

Publications Citing Use of MedChemExpress (MCE) DDP-38003

Alle Histone Demethylase Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Publications (1)

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

DDP-38003 Related Classifications

HY-19612 Related Classifications