DQP-1105
Based on 1 publication(s) in Google Scholar
DQP-1105 is a potent noncompetitive NMDA receptor antagonist. DQP-1105 inhibits GluN2C- and GluN2D-containing receptors (IC50=7.0 and 2.7 μM, respectively). The IC50 values are at least 50-fold lower than those for recombinant GluN2A-, GluN2B-, GluA1-, or GluK2-containing receptors.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.00%
- CAS. Nr.: 380560-89-4
- Formel: C29H24BrN3O4
- Molecular Weight:558.42
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Speicherung:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
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Publications Citing Use of MedChemExpress (MCE) DQP-1105
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Biologische Aktivität
Chemical Information
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CAS. Nr. 380560-89-4
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Appearance Solid
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Molecular Weight 558.42
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Formel C29H24BrN3O4
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Color White to off-white
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SMILES
O=C(CCC(N1N=C(CC1C2=CC=C(C=C2)Br)C3=C(C4=CC=CC=C4)C5=C(C=CC(C)=C5)NC3=O)=O)O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
Publications (1)
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Journal Impact Factor
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Most Recent
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Sleep Med
Cerebellar GluN2C protects against sleep deprivation-induced cognitive impairment and motor incoordination. [Abstract]2025 Nov 8:137:108648. PMID: 41223665
Lösungsmittel & Löslichkeit
DMSO : 10 mg/mL (17.91 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Reinheit & Dokumentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
Verweise
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7908 mL | 8.9538 mL | 17.9077 mL | 44.7692 mL |
| 5 mM | 0.3582 mL | 1.7908 mL | 3.5815 mL | 8.9538 mL | |
| 10 mM | 0.1791 mL | 0.8954 mL | 1.7908 mL | 4.4769 mL | |
| 15 mM | 0.1194 mL | 0.5969 mL | 1.1938 mL | 2.9846 mL |
DQP-1105 Related Classifications
HY-107711 Related Classifications
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