country

Change Language

EN - English
FR - Français
DE - Deutsch
ES - Español
JA - 日本語
KO - 한국어

Country or Region:

United States

Product Name	Size / Unit Price	Qty

Total: USD 0.00 Checkout

Art. -Nr.: HY-N19772

Copy Link Print Information

Echiguanine B

Echiguanine B is a phosphatidylinositol-4-kinase (PI4K) inhibitor with an IC₅₀ of 0.11 μg/mL against human targets. Echiguanine B inhibits phosphatidylinositol-4-kinase activity in the cell membranes of epithelial cancer cells. Echiguanine B can be used in cancer-related research.

Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.

CAS. Nr.: 137319-26-7
Formel: C₁₀H₁₄N₆O₂
Molecular Weight:250.26

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Echiguanine B Chemical Structure

CAS. Nr.: 137319-26-7

Größe

Preis

Verfügbarkeit

Menge

Amount: USD 0.00

* Bitte wählen Sie Menge, bevor Sie Artikel hinzufügen.

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
- Cellular Effect
- In Vitro
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

IC₅₀ & Target

^[1]

PI4K

0.11 μg/mL (IC₅₀)

Alle PI4K Isoform-spezifische Produkte anzeigen :

Cellular Effect

Cell Line	Type	Value	Description	References
A-431	IC₅₀	0.18 μg/mL Compound: 2 (echiguanine B)	Inhibition of Phosphatidylinositol 4-kinase of human epidermoid carcinoma A431 cells Inhibition of Phosphatidylinositol 4-kinase of human epidermoid carcinoma A431 cells	10.1016/S0960-894X(97)00122-4
A-431	IC₅₀	0.11 μg/mL Compound: 2, Echiguanine B	Inhibition of phosphatidylinositol 4-kinase in human A431 cell membrane by liquid scintillation counting Inhibition of phosphatidylinositol 4-kinase in human A431 cell membrane by liquid scintillation counting	[PMID: 1666120]

In Vitro

Lipid Metabolism

Echiguanine B (20 min at 20°C) inhibits phosphatidylinositol-4-kinase from A431 cell membranes with an IC₅₀ of 0.11 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Related Protocols :

Chemical Information

CAS. Nr. 137319-26-7
Molecular Weight 250.26
Formel C₁₀H₁₄N₆O₂
SMILES

O=C1N=C(NC2=C1C(C(NCCCN)=O)=CN2)N
Structure Classification
- Others
Initial Source
- Microorganism
STREPTOMYCES SP.
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Nishioka H, et al. Isolation and structure determination of novel phosphatidylinositol kinase inhibitors, echiguanines A and B, from Streptomyces sp. Journal of natural products. 1991;54(5):1321-5. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

Minimum order quantity

100 mg

Angebot einholen Auf Lager

Other size

Angebot einholen