Ganoderic acid Y
Based on 1 Customer Validation
Ganoderic acid Y is a α-glucosidase inhibitor with an IC50 of 170 μM for yeast α-glucosidase. Ganoderic acid Y inhibits enterovirus 71 (EV71) replication through blocking EV71 uncoating.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Reinheit: 98.0%
- CAS. Nr.: 86377-52-8
- Formel: C30H46O3
- Molecular Weight:454.68
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Speicherung:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
11 μM
Compound: 64
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Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
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[PMID: 23092389] |
| K562 | IC50 |
17.5 μM
Compound: 25
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Cytotoxicity against human K562 cells by MTT method
Cytotoxicity against human K562 cells by MTT method
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[PMID: 26287401] |
| PC-3 | IC50 |
179.8 μM
Compound: 25
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Cytotoxicity against human PC3 cells by MTT method
Cytotoxicity against human PC3 cells by MTT method
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[PMID: 26287401] |
Ganoderic acid Y significantly inhibits the replication of the viral RNA (vRNA) of EV71[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 86377-52-8
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Appearance Solid
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Molecular Weight 454.68
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Formel C30H46O3
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Color White to off-white
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SMILES
CC1(C)[C@@H](O)CC[C@]2(C)C3=CC[C@]4(C)[C@@H]([C@H](C)CC/C=C(C)/C(O)=O)CC[C@](C)4C3=CC[C@@]12[H]
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Structure Classification
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Initial Source
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Reinheit & Dokumentation
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Data Sheet (268 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Handling Instructions (2659 KB)
Verweise
[1]. Chen XQ, et al. Lanostane triterpenes from the mushroom Ganoderma resinaceum and their inhibitory activities against α-glucosidase. Phytochemistry. 2018 May;149:103-115. [Content Brief]
[2]. Zhang W, et al. Antiviral effects of two Ganoderma lucidum triterpenoids against enterovirus 71 infection. Biochem Biophys Res Commun. 2014 Jul 4;449(3):307-12. [Content Brief]
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Ganoderic acid Y Related Classifications
HY-125713 Related Classifications
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