MCL-524
MCL-524 is a highly selective full agonist of the dopamine D2 receptor with a Kd value of 1.34 nM. MCL-524 specifically binds to the high-affinity state of the dopamine D2 receptor; this binding is abolished by guanylylimidodiphosphate, and it can distinguish between D2high and D2low sites. MCL-524 is applicable to research related to Parkinson's disease and schizophrenia.
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- CAS. Nr.: 1863967-01-4
- Formel: C21H24FNO3
- Molecular Weight:357.42
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Biologische Aktivität
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D2 Receptor 1.34 nM (Kd) |
MCL-524 competes with [3H]MCL-524 for binding to the human long-form D2 receptor expressed in CHO cells, with an inhibition constant (Ki) of 2.28 nM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS. Nr. 1863967-01-4
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Molecular Weight 357.42
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Formel C21H24FNO3
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SMILES
OC1=CC=C2C(C3=C4C(CCN(CCC)[C@]4([H])C2)=CC(OCCF)=C3)=C1O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
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