MEY-003
MEY-003 is an Autotaxin(ATX) inhibitor with EC50s of 460 nM and 1.09 μM for hATX-β and hATX-ɣ (analysis with LPC18:1). MEY-003 behaves as a non-competitive inhibitor with K iof 432 nM. MEY-003 can be used for targeted ATX-related disease research .
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- CAS. Nr.: 3047891-88-0
- Formel: C22H21NO4
- Molecular Weight:363.41
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Chemical Information
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Help & FAQs
Biologische Aktivität
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Autotaxin |
MEY-003 (10 μM, 30 min) blocks lysophosphatidic acid (LPA) signaling, and reduces LPA1 receptor internalization in HeLa cell[1].
MEY-003 (100 μM, 0-24 h) shows no cytotoxicity effects in HeLa and HEK293 cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:HeLa and HEK293 cells
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Concentration:100 μM
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Incubation Time:0-24 h
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Result:Showed non-cytotoxic after prolonged treatment (up to 24 h) at 100 μM with HeLa cells or HEK293 cells.
Chemical Information
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CAS. Nr. 3047891-88-0
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Molecular Weight 363.41
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Formel C22H21NO4
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SMILES
OC1=C2C(OC(C3=CN(CCCCC)C4=C3C=CC=C4)=CC2=O)=CC(O)=C1
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
MEY-003 Related Classifications
HY-149716 Related Classifications
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