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Art. -Nr.: HY-152951

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Palmostatin M

Palmostatin M is a Ras signaling modulator that targets acyl-protein thioesterase 1 (APT1) and 2 (APT2) in cells, with an IC₅₀ of 2.5 nM for APT1. Palmostatin M interferes with the depalmitoylation cycle of Ras and downregulates the overall Ras signaling pathway. Palmostatin M can be used in cancer-related research.

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CAS. Nr.: 1351669-68-5
Formel: C₂₂H₄₃NO₄S
Molecular Weight:417.65

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Palmostatin M Chemical Structure

CAS. Nr.: 1351669-68-5

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Biologische Aktivität

Beschreibung

Alle Ras Isoform-spezifische Produkte anzeigen :

In Vitro

Palmostatin M potently inhibits recombinant human APT1 in a biochemical assay with an IC₅₀ of 2.5 nM^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS. Nr. 1351669-68-5
Molecular Weight 417.65
Formel C₂₂H₄₃NO₄S
SMILES

C(CCCS(CCCN(C)C)(=O)=O)[C@H]1[C@H](CCCCCCCCCC)C(=O)O1
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Handling Instructions (2659 KB)

Verweise

[1]. Rusch M, et al. Identification of acyl protein thioesterases 1 and 2 as the cellular targets of the Ras-signaling modulators palmostatin B and M. Angew Chem Int Ed Engl. 2011;50(42):9838-9842. [Content Brief]

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

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How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Palmostatin M

Alle Ras Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

Palmostatin M Related Classifications

HY-152951 Related Classifications